PORTABLE STEREO DIGITAL FUNDUS CAMERA

便携式立体数字眼底照相机

• 批准号: 6164708
• 负责人: DAVID B DUNCAN
• 金额: $ 35.23万
• 依托单位: DUNCAN TECHNOLOGIES, INC.
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-09-01 至 2002-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6164708
• 关键词: bioimaging /biomedical imaging; biological models; biomedical equipment development; clinical research; diabetic retinopathy; diagnosis design /evaluation; digital imaging; eye disorder diagnosis; eye fundus photography; eye neoplasms; fluorescein angiography; glaucoma; human subject; ophthalmoscopy; portable biomedical equipment; retina detachment; retinoblastoma; retinopathy of prematurity; stereophotography

The applicant firm proposes the development of a portable digital stereo fundus camera. The proposed camera would enhance the quality and economies of screening and providing care for degenerative diseases of the retina and choroid. The camera will be evaluated for diagnostic screening of retinal detachments, diabetic retinopathy, retinal holes, epiretinal membranes, retinalblastomas, ocular tumors, retinopathy of prematurity and glaucomatist optic disc cupping. The proposed research will result in the development of a pre-product prototype unit that achieves high resolution digital stereo fundus imaging in a hand held unit. During the Phase II research an initial prototype camera will be developed and tested by imaging a model eye and one hundred human patients. Results of this study will be used to determine necessary modifications to the camera design. These changes will be implemented and a pre-product prototype will be fabricated and tested. In a second clinical study patients from remote sites will be imaged with the camera and images transmitted to the University of California Davis Medical Center for evaluation. Ophthalmic specialists will evaluate the camera's effectiveness in a clinical setting and its usefulness in the clinical acquisition of images onsite and digital transmission to off site locations. PROPOSED COMMERCIAL APPLICATIONS: A large commercial market exists for application of the proposed instrument in screening and treatment of diabetic retinopathy, macular degeneration, and other vascular diseases of the retina. Applications include clinical and telemedicine sites at prisons, nursing homes, military sites, and retirement communities, and Native American reservations.

申请公司提议开发一种便携式数字立体眼底相机。拟议的摄像机将提高筛查的质量和经济性，并为视网膜和脉络膜的退行性疾病提供护理。该相机将用于视网膜脱离、糖尿病视网膜病变、视网膜裂孔、视网膜前膜、视网膜母细胞瘤、眼肿瘤、早产儿视网膜病变和青光眼视盘拔罐的诊断筛查。拟议的研究将导致开发一种预产品原型单元，在手持单元中实现高分辨率数字立体眼底成像。在第二阶段的研究中，将开发一台初始原型相机，并通过对一只模型眼和100名人类患者进行成像进行测试。这项研究的结果将被用来确定对相机设计的必要修改。这些改变将被实施，并将制造和测试预产品原型。在第二项临床研究中，来自偏远地区的患者将用相机进行成像，并将图像传输到加州大学戴维斯医学中心进行评估。眼科专家将评估该相机在临床环境中的有效性，以及它在临床现场图像采集和数字传输到非现场位置的有用性。建议的商业应用：建议的仪器在糖尿病视网膜病变、黄斑变性和其他视网膜血管疾病的筛查和治疗中存在巨大的商业市场。应用包括监狱、疗养院、军事地点和退休社区的临床和远程医疗地点，以及美洲原住民保留地。