PORTABLE STEREO DIGITAL FUNDUS CAMERA

申请公司建议发展一种便携式数码立体眼底相机。该摄像机将提高视网膜和脉络膜退行性疾病的筛查和护理的质量和经济性。该相机将被评估为视网膜脱离，糖尿病视网膜病变，视网膜孔，视网膜前膜，视网膜母细胞瘤，眼部肿瘤，早产儿视网膜病变和青光眼视盘拔罐的诊断筛查。提出的研究将导致开发一个产品前原型单元，在手持单元中实现高分辨率数字立体眼底成像。在第二阶段的研究中，最初的原型相机将被开发出来，并通过对一只模型眼睛和100名人类患者进行成像来进行测试。这项研究的结果将用于确定相机设计的必要修改。这些变化将被实施，并将制造和测试预产品原型。在第二项临床研究中，来自偏远地区的患者将被相机成像，并将图像传输到加州大学戴维斯医学中心进行评估。眼科专家将评估该相机在临床环境中的有效性，以及它在临床采集现场图像和数字传输到非现场位置的有用性。拟议的商业应用：拟议的仪器在筛查和治疗糖尿病视网膜病变、黄斑变性和其他视网膜血管疾病方面的应用存在巨大的商业市场。应用包括监狱、养老院、军事场所、退休社区和印第安人保留地的临床和远程医疗站点。

The applicant firm proposes the development of a portable digital stereo fundus camera. The proposed camera would enhance the quality and economies of screening and providing care for degenerative diseases of the retina and choroid. The camera will be evaluated for diagnostic screening of retinal detachments, diabetic retinopathy, retinal holes, epiretinal membranes, retinalblastomas, ocular tumors, retinopathy of prematurity and glaucomatist optic disc cupping. The proposed research will result in the development of a pre-product prototype unit that achieves high resolution digital stereo fundus imaging in a hand held unit. During the Phase II research an initial prototype camera will be developed and tested by imaging a model eye and one hundred human patients. Results of this study will be used to determine necessary modifications to the camera design. These changes will be implemented and a pre-product prototype will be fabricated and tested. In a second clinical study patients from remote sites will be imaged with the camera and images transmitted to the University of California Davis Medical Center for evaluation. Ophthalmic specialists will evaluate the camera's effectiveness in a clinical setting and its usefulness in the clinical acquisition of images onsite and digital transmission to off site locations. PROPOSED COMMERCIAL APPLICATIONS: A large commercial market exists for application of the proposed instrument in screening and treatment of diabetic retinopathy, macular degeneration, and other vascular diseases of the retina. Applications include clinical and telemedicine sites at prisons, nursing homes, military sites, and retirement communities, and Native American reservations.