DENTAL COMPOSITES BASED ON RIGID, HYPERBRANCHED POLYMERS

描述：（改编自申请人摘要）牙科复合材料 已经发现广泛用作牙科汞合金的美学替代品。然而，在这方面， 需要改进这些材料的耐久性和寿命。 因为最终的修复剂必须具有可接受的处理性能 对于牙医来说，任何用于改善修复体性能的方法 不得显著增加粘度。线性聚合物的加入 对牙科复合材料的改性提高了增塑剂的物理性能; 然而，经常观察到粘度的伴随增加， 这些材料的临床应用。然而，超支化聚合物， 一类新的高度支化的聚合物材料， 溶液或熔体粘度不会随着增加而显著增加 分子量。该提案将建立甲基丙烯酸酯化的能力， 商业超支化聚合物，以改善牙科 同时保持低的功能粘度。遵循这些 初步研究，高性能超支化聚合物，硬化虽然 分子内氢键，将被合成，以进一步提高 的属性。这些改性超支化聚合物将是 用BisGMA-TEGDMA配制，并评价物理性能 使用标准技术。据预测，超分支修改 BisGMA-TEGDMA将展示可以预期的改进性能 从高分子量聚合物，但这些材料将不会经历任何 粘度显著增加。

DESCRIPTION: (Adapted from applicant's abstract) Dental composite restoratives have found wide use as an aesthetic substitute for dental amalgams. However, there is need to improve the durability and longevity of these materials. Because the final restorative must have handling properties that are acceptable to the dentist, any method used to improve the properties of the restorative must not significantly increase the viscosity. The addition of linear polymers to dental composites increases the physical properties of restoratives; however, a concomitant increase in viscosity is often observed which impedes the clinical application of these materials. However, hyperbranched polymers, a new class of high-branched polymeric materials, maintain relatively low solution or melt viscosities that do not increase significantly with increases in molecular weight. This proposal will establish the ability of methacrylated commercial hyperbranced polymers to improve the properties of dental restoratives while maintaining a low, functional viscosity. Following these preliminary studies, high performance hyperbranced polymers, rigidified though intramolecular hydrogen bonding, will be synthesized to further enhance the properties of the restoratives. These modified hyperbranced polymers will be formulated with BisGMA-TEGDMA and the physical properties will be evaluated using standard techniques. It is anticipated that the hyperbranced modified BisGMA-TEGDMA will demonstrate the improved properties that can be expected from high molecular weight polymers but these materials will not experience any significant increase in viscosity.