DENTAL COMPOSITES BASED ON RIGID, HYPERBRANCHED POLYMERS

基于刚性、超支化聚合物的牙科复合材料

基本信息

批准号：
6175921
负责人：
SCOTT R SCHRICKER
金额：
$ 3.7万
依托单位：
OHIO STATE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
1999
资助国家：
美国
起止时间：
1999-08-01 至 2002-07-31
项目状态：
已结题

项目摘要

DESCRIPTION: (Adapted from applicant's abstract) Dental composite restoratives have found wide use as an aesthetic substitute for dental amalgams. However, there is need to improve the durability and longevity of these materials. Because the final restorative must have handling properties that are acceptable to the dentist, any method used to improve the properties of the restorative must not significantly increase the viscosity. The addition of linear polymers to dental composites increases the physical properties of restoratives; however, a concomitant increase in viscosity is often observed which impedes the clinical application of these materials. However, hyperbranched polymers, a new class of high-branched polymeric materials, maintain relatively low solution or melt viscosities that do not increase significantly with increases in molecular weight. This proposal will establish the ability of methacrylated commercial hyperbranced polymers to improve the properties of dental restoratives while maintaining a low, functional viscosity. Following these preliminary studies, high performance hyperbranced polymers, rigidified though intramolecular hydrogen bonding, will be synthesized to further enhance the properties of the restoratives. These modified hyperbranced polymers will be formulated with BisGMA-TEGDMA and the physical properties will be evaluated using standard techniques. It is anticipated that the hyperbranced modified BisGMA-TEGDMA will demonstrate the improved properties that can be expected from high molecular weight polymers but these materials will not experience any significant increase in viscosity.

描述：（改编自申请人的摘要）牙科复合恢复已发现广泛用作牙科融合的美学替代品。然而，需要提高这些材料的耐用性和寿命。因为最终修复剂必须具有可接受的处理属性对于牙医，任何用于改善修复的特性的方法不得显着提高粘度。线性聚合物的添加牙科复合材料增加了恢复的物理特性；但是，经常观察到粘度的同时增加，这会阻碍这些材料的临床应用。但是，超支聚合物，一个新的高分支聚合材料，保持相对较低溶液或融化粘度不会随着增加而显着增加在分子量中。该建议将确定甲基丙烯酸的能力商业超桥聚合物以改善牙齿的特性在保持低功能粘度的同时恢复。遵循这些初步研究，高性能超爆发聚合物，虽然僵化分子内氢键将合成，以进一步增强修复的特性。这些修饰的超泡聚合物将是将评估用Bisgma-Tegdma配制的物理特性使用标准技术。预计超桥的修改 Bisgma-Tegdma将证明可以预期的改进特性从高分子重量聚合物中，但这些材料不会经历任何粘度的显着增加。