PORTABLE LOW-COST ANALYZER FOR TOXIC METAL AEROSOLS

便携式低成本有毒金属气溶胶分析仪

• 批准号: 6178644
• 负责人: Clifford D Jolly
• 金额: $ 35.87万
• 依托单位: ELS TECHNOLOGY, INC.
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-09-30 至 2001-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6178644
• 关键词: aerosols; air filtration; air sampling /monitoring; beryllium; biomedical equipment development; chromium; electrical measurement; lead; metal poisoning; metals; monitoring device; occupational health /safety; portable biomedical equipment

A portable instrument for proactive prevention of occupational exposure to metals and metal-containing dusts is proposed. The technical approach is innovative and based on analytical principles. The program will result in a tool that improves both routine exposure monitoring and toxicological research capabilities by providing less expensive, more rapid, higher- quality data. Current methods cannot prevent respiratory exposure in real time, and are costly to implement. The proposed approach simultaneously reduces risk of exposure and lowers compliance costs. Phase I and related work have demonstrated a simple method to analyze beryllium, chromium, and lead, which are particularly toxic metals used throughout government and industry. An innovative method to extract metals from sample filters, combined with a highly sensitive and selective voltammetric detection technique was developed and demonstrated in the presence of potential interferences. In Phase II, a personal breathing zone filter analyzer for on-site use will be fabricated and tested using industrial filter samples to validate performance under typical field conditions. Instrument end-user costs is estimated and 15K dollars, with on-site sample turn- around times of 5-20 minutes. The method is simple to operate and does not expose field personnel to hazardous materials. PROPOSED COMMERCIAL APPLICATION Government and industry have been clear and persistent in communicating the need for more rapid, lower-cost methods for analyzing respirable toxic metals. Over 10,000 applications exist in electronics, mining, military, coatings, and environmental industries.

提出了一种可主动预防职业暴露于金属和金属灰尘的便携式工具。 技术方法是创新的，并且基于分析原理。 该计划将通过提供较便宜，更快，更高质量的数据来改善常规暴露监测和毒理学研究能力的工具。 当前的方法无法实时防止呼吸道暴露，并且实施昂贵。 拟议的方法同时降低了暴露的风险，并降低了合规成本。 第一阶段和相关的工作表明了一种简单的方法来分析铍，铬和铅，这些方法是在整个政府和工业中使用的特别有毒金属。 从样品过滤器中提取金属的创新方法与高度敏感和选择性的伏安检测技术相结合，并在存在潜在干扰的情况下得到了证明。 在第二阶段，将使用工业过滤器样品制造和测试个人呼吸区过滤器分析仪，以在典型的现场条件下验证性能。 仪器最终用户的成本估计为15k美元，现场样本转盘约为5-20分钟。 该方法易于操作，并且不会使现场人员暴露于危险材料中。拟议的商业应用政府和行业在传达需要更快，更低成本的方法来分析可呼吸有毒金属的需求方面已经清楚而持久。 在电子，采矿，军事，涂料和环境行业中，有10,000多种应用。