TRAINING IN CARDIOVASCULAR RESEARCH

培训计划的目的是为心血管医学的学术生涯做好准备。该项目强调心血管疾病分子生物学和遗传学方面的培训。大多数学员将是内科住院医师的直接毕业生，进入我们为期四年的心脏病学研究项目，包括24个月的临床培训（不受本资助申请的支持）和24个月的研究培训。有些受训者将研究训练的期限延长至三或四年。建立核心课程。说教式教学包括分部会议、研讨会、专题讲座系列以及学校和大学课程。在大多数情况下，每个受训者将主要与一名教员合作，在一个明确界定的领域接受研究培训，为期两到三年。在这一资助期内，该项目已经改变，以强调在8个基础研究实验室进行分子生物学和遗传学的培训机会，每个实验室都与临床研究项目和一个基于基因的患者治疗项目有关。像过去一样，15名额外的教员将提供全面的研究选择，但我们希望大多数研究员选择分子生物学和遗传学培训，或者将基本遗传发现转化为临床研究的培训。基础和临床研究之间的联系是我们项目的一个突出主题，这是该医学院基础和临床心血管科学家长期合作的结果。培训设施包括医学院的实验室、Wintrobe研究大楼、大学研究部分、诺拉·埃克尔斯·哈里森研究和培训学院、埃克尔斯人类遗传学大楼、生物医学聚合物研究大楼、亨茨曼癌症研究所和弗吉尼亚州盐湖医疗中心；以及犹他大学和弗吉尼亚州盐湖城医疗中心的临床设施。所有主要培训学院和大多数其他参与学院都有广泛的联邦和其他研究资助。该奖学金的毕业生有能力设计和执行以假设为导向的生物医学研究项目，并有资格在学术项目中担任全职医学院教员。在这个由nsa支持的项目的前14年里，我们的学员进入学术职位的比例达到了81%。

The purpose of the training program is to prepare physicians for academic careers in cardiovascular medicine. The program emphasizes training in molecular biology and genetics of cardiovascular disease. Most trainees will be immediate graduates of internal medicine residencies entering our four-year fellowship in cardiology, composed of 24 months of clinical training (not supported by this grant request) and 24 months of research training. Some trainees will extend the period of research training to three or four years. A core curriculum is established. Didactic teaching includes divisional conferences, seminars, topically organized lecture series, and School and University courses. Each trainee will associate primarily with one faculty member to receive research training in a well-circumscribed area for two or three years in most cases. The program has been changed for this grant period to emphasize training opportunities in molecular biology and genetics in eight basic research laboratories, each with ties to clinical research programs, and in one gene-based patient therapy program. Fifteen additional faculty will offer a full compliment of research choices as in the past, but we expect most fellows to opt for molecular biology and genetic training or training in the translation of basic genetic discoveries to the bedside. The link between basic and clinical research is a prominent theme in our program, a result of long standing collaborations between basic and clinical cardiovascular scientists in this medical school. Training facilities include laboratories in the Medical School, the Wintrobe Research Building, University Research Part, the Nora Eccles Harrison Research and Training Institute, the Eccles Human Genetics Building, the Biomedical Polymers Research Building, the Huntsman Cancer Institute and the Salt Lake VA Medical Center; and clinical facilities in the University of Utah and Salt Lake VA Medical Centers. All of the primary training faculty and most other participating faculty have extensive federal and other research funding. Graduates of this fellowship are capable of designing and performing hypothesis-oriented biomedical research projects and are qualified for full-time medical school faculty appointments in academic programs. During the previous 14 years of this NRSA-supported program, we have achieved an 81% ate of entry into academic positions by our trainees.