CLINICAL RESEARCH CURRICULUM AND MENTORSHIP PROGRAM

约翰霍普金斯大学临床研究研究生培训计划（GTPCI）于1993年启动，是该大学医学院和公共卫生学院的共同努力。该项目在五年内培养了45名内科研究人员进入为期一年的教学课程，然后进行至少两年的临床研究指导，最终发表论文并获得硕士或博士学位。我们现在建议在新的NIH支持机制下，为这一模式项目提供强化的管理、指导和课程结构，并评估其在培养富有成效的职业研究者方面的成功。新的特点包括课程元素的扩展，包括基于网络的学习，将核心课程扩展到包括教师和博士后在内的更广泛的受众，对教育成果进行正式评估，加强少数民族的招聘和实习生的保留，以及丰富教师和整个学术界的临床研究经验。该项目的长期目标是加强、提高和评估培养优秀临床研究人员的模式，我们已经获得了相当多的经验，并将其一些好处扩展到约翰霍普金斯大学内外更广泛的临床研究人员群体。具体目标是：(1)为正在进行的GTPCI提供和加强行政和课程结构；(2)评估GTPCI模式和相关项目在培养成功的职业研究者方面的成功程度；(3)为约翰霍普金斯大学内外更广泛的博士后、教师和活跃的临床研究人员提供临床研究方面的短期课程。我们期望这些增强和扩展将提高我们机构临床研究未来职业的可见度，有效性和成功。

The Johns Hopkins Graduate Training Program in Clinical Investigation (GTPCI) was initiated in 1993 as a joint effort of the University's Schools of Medicine and Public Health. The Program has matriculated 45 physician-investigators over five years into a year-long didactic curriculum which is then followed by at least two years of mentored clinical research leading to thesis publication and the award of either an M.Sc. or Ph.D. degree. We now propose under this new NIH support mechanism to provide enhanced administrative, mentoring, and curriculum structures for this model program, and to evaluate its success in generating productive career investigators. New features include expansion of curriculum elements, including Web-based learning, extension of the core curriculum to a broader audience including faculty and postdoctoral fellows, formal appraisal of educational outcomes, enhancement of minority recruitment and trainee retention, and enrichment experiences in clinical investigation for faculty and the entire academic community. The long-term objective of this project is to strengthen, enhance, and evaluate a model for training superior clinical investigators, with which we already have gained considerable experience, and to extend some of its benefits to a broader group of clinical investigators both within and external to Johns Hopkins. The specific aims are: (1) to provide and enhance an administrative and curriculum structure for the ongoing GTPCI; (2) to evaluate the success of the GTPCI model and related programs in generating successful career investigators; and (3) to provide shorter term curricula in aspects of clinical investigation to a broader group of postdoctoral fellows, faculty and active clinical investigators both within and external to Johns Hopkins. We expect that these enhancements and extensions will heighten the visibility, effectiveness and success of future careers in clinical investigation at our institution.