Development of a highly potent, fully human anti-GM-CSF monoclonal antibody

开发高效、全人源抗 GM-CSF 单克隆抗体

• 批准号: nhmrc : 400144
• 负责人: John Schrader
• 金额: $ 22.27万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Development Grants
• 财政年份: 2007
• 资助国家: 澳大利亚
• 起止时间: 2007-01-01 至 2007-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/development-highly-potent-monoclonal-antibody/95084
• 关键词: Development; highly; potent; fully; human

Many diseases, such as arthritis, have unwanted inflammatory reactions. Better drugs are needed to control inflammation. A powerful antibody to a significant pro-inflammatory cytokine will be generated; this antibody will be especially designed so that it will not be rejected by patients. Because of its properties it will cost the community less than similar therapeutics. Because inflammatory diseases are common many patients will benefit from our therapeutic.

许多疾病，如关节炎，都有不必要的炎症反应。需要更好的药物来控制炎症。将产生一种针对一种重要的促炎细胞因子的强大抗体；这种抗体将被特别设计，使其不会被患者排斥。由于它的特性，它将比类似的疗法花费更少的社区费用。由于炎症性疾病很常见，许多患者将从我们的治疗中受益。