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CORE--MOLECULAR GENETICS

CORE--MOLECULAR GENETICS
核心--分子遗传学
批准号:
6110552
负责人:
MARK LEPPERT
金额:
$24.67万
依托单位国家:
美国
项目类别:
财政年份:
1999
资助国家:
美国
项目状态:
已结题
起止时间:
1999-02-01 至 2000-01-31

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中文摘要
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英文摘要
Our hypothesis is that molecular variants at some loci affecting blood pressure regulation predispose individuals to the development of essential hypertension. Multifactorial determination and heterogeneity suggest that several genes may account for a predominant fraction of this genetic component. In this H-SCOR, we will be examining selected genes in patients with salt/volume sensitive hypertension as outlined in Projects 1 and 2. Analysis of genetic linkage, direct search for mutations, and genotyping at select loci may help in identifying 'genetic' subgroups for physiological studies in these two projects. This core will also assist investigators in projects 3-5 in marker development or other molecular genetic approaches as the need arise.
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RESTLESS LEGS SYNDROME
  • 批准号:
    7718507
  • 项目类别:
  • 资助金额:
    $0.21万
  • 财政年份:
    2008
  • 负责人:
    MARK LEPPERT
  • 依托单位:
RESTLESS LEGS SYNDROME
  • 批准号:
    7604965
  • 项目类别:
  • 资助金额:
    $1.31万
  • 财政年份:
    2007
  • 负责人:
    MARK LEPPERT
  • 依托单位:
RESTLESS LEG SYNDROME
  • 批准号:
    7376475
  • 项目类别:
  • 资助金额:
    $0.97万
  • 财政年份:
    2006
  • 负责人:
    MARK LEPPERT
  • 依托单位:
CORE--MOLECULAR GENETICS
  • 批准号:
    7010662
  • 项目类别:
  • 资助金额:
    $18.21万
  • 财政年份:
    2005
  • 负责人:
    MARK LEPPERT
  • 依托单位:
海外基金