STRUCTURAL PROPERTIES OF MEMBRANES

膜的结构特性

• 批准号: 6258789
• 负责人: ROBERT BITTMAN
• 金额: $ 0.08万
• 依托单位: MICHIGAN STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-06-01 至 1999-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6258789
• 关键词: biological products; biomedical resource; biotechnology; proteins; technology /technique development

This project seeks to examine the interaction of cholesterol with other lipids, including glycero- and sphingolipids, and cerebrosides. Synthetic analogs of natural lipids are synthesized and used in membrane studies. It is essential to obtain full characterization of the lipids synthesized. FAB-MS, FAB-CAD-MS/MS and FAB-CAD-MS/MS and exact mass measurements were all used to characterize more than 75 compounds.

该项目旨在检查胆固醇与 其他脂质，包括甘油和鞘脂，以及大脑。 天然脂质的合成类似物合成并用于 膜研究。 必须完全表征 脂质合成。 FAB-MS，FAB-CAD-MS/MS和FAB-CAD-MS/MS和 精确的质量测量都被用来表征超过75 化合物。