TREATMENT OF HEART FAILURE IN OLDER HUMANS

老年人心力衰竭的治疗

• 批准号: 6297107
• 负责人: Mark A Supiano
• 金额: $ 0.02万
• 依托单位: UNIVERSITY OF MICHIGAN AT ANN ARBOR
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-12-01 至 1999-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6297107
• 关键词: beta adrenergic receptor; beta antiadrenergic agent; cardiovascular disorder chemotherapy; clinical research; clinical trials; congestive heart failure; drug screening /evaluation; human old age (65+); human subject; human therapy evaluation; sympathetic nervous system

This proposal will identify the extent to which therapy with a beta-adrenergic receptor antagonist will enhance the functional independence of older humans with congestive heart failure. In addition, the effect of this intervention to modify sympathetic nervous system function will be tested as a pathophysiologic mechanism which may contribute to the response to treatment.

该提案将确定β-肾上腺素能受体拮抗剂治疗在多大程度上增强老年充血性心力衰竭患者的功能独立性。 此外，将检测这种干预对交感神经系统功能的影响，作为可能有助于治疗反应的病理生理机制。