VANCOMYCIN ADMINISTERED DURING HEMODIALYSIS WITH CELLULOSE TRIACETATE DIALYZERS

本研究旨在进一步研究阿司匹林的药代动力学。 肾功能不全患者血液透析中万古霉素的应用 使用三醋酸纤维素钠(CT)透析器。万古霉素15 mg/kg剂量 在血液透析期间给予30毫克/公斤，在血液透析期间给予15毫克/公斤 血液透析治疗将进行比较。血浆和透析液 在8天的研究期内，万古霉素的浓度分布将是 下定决心。

This study is designed to further examine the pharmacokinetics of vancomycin in volunteers with renal dysfunction requireing hemodialysis with cellulose triacetate (CT) dialyzers. Vancomycin doses of 15 mg/kg and 30 mg/kg given during hemodialysis and 15 mg/kg given between hemodialysis treatments will be compared. The plasma and dialysate vancomycin concentration profiles over the 8 day study period will be determined.