NEUROHORMONAL REGULATION OF SYSTEMATIC HEMOSTATIC FUNCTION

系统止血功能的神经激素调节

• 批准号: 6114355
• 负责人: BRIAN A ROSENFELD
• 金额: $ 2.06万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-12-01 至 1999-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6114355
• 关键词: hemostasis; hemostatics; hormone regulation /control mechanism; human subject; lactic acidosis; neurohormones

We have attempted to extend our initial observations that the stress hormone infusion caused the development of a lactic acidemia in normal volunteers. We have done this by altering the combinations of stress hormone infusion to see whether individual or combinations of hormones are responsible for the acidemia. We are near completion of these experiments which appear to demonstrate that vasopressin and angiotensin have no effect; and that epinephrine may be the responsible hormone.

我们试图扩大我们最初的观察，即压力 激素注射导致正常人发生乳酸血症 志愿者。我们通过改变压力的组合来做到这一点 荷尔蒙输注，看看是单独还是激素组合 是导致酸血症的原因。我们即将完成这些工作。 有实验表明，血管加压素和血管紧张素 没有效果；而肾上腺素可能是负责的荷尔蒙。