NEUROHORMONAL REGULATION OF SYSTEMATIC HEMOSTATIC FUNCTION

系统止血功能的神经激素调节

• 批准号: 6275590
• 负责人: BRIAN A ROSENFELD
• 金额: $ 2.01万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-12-01 至 1998-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6275590
• 关键词: hemostasis; hemostatics; hormone regulation /control mechanism; human subject; lactic acidosis; neurohormones

We have attempted to extend our initial observations that the stress hormone infusion caused the development of a lactic acidemia in normal volunteers. We have done this by altering the combinations of stress hormone infusion to see whether individual or combinations of hormones are responsible for the acidemia. We are near completion of these experiments which appear to demonstrate that vasopressin and angiotensin have no effect; and that epinephrine may be the responsible hormone.

我们试图扩展我们最初的观察， 激素输注引起正常人乳酸血症的发展， 志愿者 我们通过改变压力的组合 激素注射，看看是否单独或组合激素 导致了酸血症 我们即将完成这些 这些实验似乎证明了血管加压素和血管紧张素 没有影响;肾上腺素可能是负责的激素。