NUTRITIONAL THERAPY OF CHRONIC RENAL FAILURE IN OUTPATIENTS

成人肾病综合征的最佳膳食蛋白质摄入量尚未确定；蛋白质含量极低的饮食被认为是禁忌。然而，26名患有肾病综合征的成年人被规定了非常低蛋白质的饮食（0.3 g/kg），补充10-20 g/天的必需氨基酸（或者，在少数情况下，酮酸），平均持续10个月。在中度或重度肾功能衰竭的患者中，蛋白尿、血清白蛋白和血清胆固醇的平均水平略有改善。在肾功能不太严重的患者中，有3人没有改善，但有5人在接下来的几个月里，从开始节食开始，他们的肾病综合征完全或几乎完全缓解。其中4人最终恢复正常饮食，没有肾病综合征复发。

Optimal dietary protein intake for adults with the nephrotic syndrome has not yet been established; very-low protein diets are believed to be contraindicated. Nevertheless, 26 adults with the nephrotic syndrome were prescribed a very low protein diet (0.3 g/kg) supplemented with 10-20 g/day of essential amino acids (or, in a few cases, ketoacids) for an average of 10 months. In patients with moderate or severe renal failure, modest improvement was seen (on the average) in proteinuria, serum albumin, and sefum cholesterol. In patients with less severe renal failure, three failed to improve, but five showed complete or nearly complete remission of their nephrotic syndrome during the ensuing months, beginning with the start of the diet. Four of them eventually resumed normal diets without recurrence of nephrotic syndrome.