DYNAMICS OF GROWTH HORMONE SECRETION IN PITUITARY GLAND DYSFUNTION

垂体功能障碍中生长激素分泌的动态

• 批准号: 6115245
• 负责人: BAHA M ARAFAH
• 金额: $ 1.92万
• 依托单位: CASE WESTERN RESERVE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-12-01 至 1999-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6115245
• 关键词: acromegaly; adolescence (12-20); clinical research; endocrine disorder chemotherapy; gigantisms; hormone regulation /control mechanism; human subject; human therapy evaluation; longitudinal human study; pituitary disorders; secretion; skeletal disorder chemotherapy; somatotropin

Dynamics of growth hormone secretion are studied in patients with pituitary gland dysfunction before and on multiple occasions after therapeutic interventions. The emphasis is primarily on patients with acromegaly or gigantism. The project is now following patients longitudinally. The patients studied as children 15-20 years ago are being assessed annually as adults to evaluate the long term efficacy of the surgical intervention.

在治疗干预之前和之后多次研究垂体功能障碍患者的生长激素分泌动力学。 重点主要是肢端肥大症或肢端肥大症患者。 该项目目前正在纵向跟踪患者。 15-20年前作为儿童研究的患者每年作为成人进行评估，以评价手术干预的长期疗效。