THEORETICAL STUDIES OF SOLVATION OF NUCLEIC ACID BASES

核酸碱基溶解的理论研究

• 批准号: 6280142
• 负责人: JAMES W CALDWELL
• 金额: $ 0.03万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-07-01 至 1999-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6280142
• 关键词: biological products; biomedical resource; model design /development; nucleic acids; proteins; technology /technique

Our study entails determination of the effect of different solvent models on the free energy perturbation of the nucleic acid bases amongst themselves. The goal is to understand the partition coefficient between water and chloroform. Molecular graphics is necessary to evaluate the validity of the various solvent models and will be used in the presentation of the results in future publications.

我们的研究需要测定不同溶剂的影响。 核酸碱基自由能微扰模型 在他们之间。目标是了解分区 水和氯仿之间的系数。分子图形学是 有必要评估各种溶剂模型的有效性 将在今后的结果展示中使用 出版物。