MAPPING THE INTERACTIONS OF RECA WITH DNA

阿祖玛实验室正在努力了解 DNA重组反应的机理。他们的努力是集中的 关于RecA催化的同源复合反应。MALDI-离子 用捕集质谱仪确定了一个单一的结合部位 利用光交联法将DNA滞留在E.Coli RecA上。一篇论文 描述确定地点的分析方面 交联性(秦和柴特，肛门。化学。69,4002-4009,1997)。

The Adzuma Laboratory is making an effort to understand the mechanisms of DNA recombination reactions. Their efforts are focused on the homologous recombination reaction catalyzed by RecA. MALDI-ion trap mass spectrometry was used to confirm a binding site of single stranded DNA on E. Coli RecA using photo-crosslinking. A paper describing analytical aspects of the determination of the site of crosslinking (Qin and Chait, Anal. Chem. 69,4002-4009, 1997).