THEORETICAL STUDIES OF PROTEINS, NUCLEIC ACIDS & SMALL MOLECULES

蛋白质、核酸的理论研究

• 批准号: 6119222
• 负责人: PETER A KOLLMAN
• 金额: $ 0.54万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-07-01 至 2000-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6119222
• 关键词: biological products; biomedical resource; enzymes; hormones; model design /development; nucleic acids; proteins; technology /technique

My research group and I have continued to use the Computer Graphics Laboratory for visualization of proteins, nucleic acids and host- guest systems, as well as the results of simulations of these systems. We make extensive use of the stereo capabilities to view the molecular interactions with the goal of understanding protein folding, structure based ligand design and the mechanism of enzyme catalyzed reactions. We have publishd in the range of 15 papers this year which acknowledge the use of the CGL facilities.

我和我的研究小组继续使用计算机 图形实验室用于蛋白质、核酸和 主客体系统，以及这些模拟的结果 系统. 我们广泛使用立体声功能来查看 分子间的相互作用，目的是了解蛋白质折叠， 基于结构的配体设计及酶催化的机理 反应. 今年我们有15篇论文发表， 确认使用CGL设施。