GLOBAL MAPPING OF XAS DATA STRUCTURE OF ACTIVE SITE OF COBALAMIN ENZYMES

钴胺素酶活性位点 XAS 数据结构的全局图谱

• 批准号: 6205768
• 负责人: EVA SCHEURING
• 金额: --
• 依托单位: ALBERT EINSTEIN COLLEGE OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-09-01 至 2000-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6205768
• 关键词: biological products; biomedical resource; enzymes; spectrometry

We have also obtained EXAFS data on model low spin ferric compounds prepared by Henry Jackson and Prof. Julia Kovacs of the Department of Chemistry, University of Washington. These complexes have a ligand with a N3S2 donor set and can be prepared as a binary low spin iron (III) complex (a rare example of five-coordinate iron (III) or as ternary, six-coordinate complexes with a variety of auxilliary ligands including azide and nitric oxide. The EXAFS and edge intensities of these complexes are being compared to those of nitrile hydratase to gain further insight into the coordination of iron in the enzyme.

我们还获得了模型低自旋铁离子的EXAFS数据