ECHO PLANAR CONTRAST ENHANCED 3D MR ANGIOGRAPHY

回波平面对比增强 3D MR 血管造影

• 批准号: 6123000
• 负责人: MARCUS T ALLEY
• 金额: $ 0.03万
• 依托单位: STANFORD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-01-01 至 2000-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6123000
• 关键词: bioimaging /biomedical imaging; biomedical resource; magnetic resonance imaging; radiology; urinary tract

Introduction: The purpose of this study was assessment of the ability of techniques of Cine-phase contrast MRI using rapid spiral acquisition to measure normal human renal blood flow in vivo. Fifteen normal volunteers were studies with Cine-phase contrast MRI. Methods: A breathheld technique employing rapid spiral acquisition [Spiral-PC], and a Cine-PC technique which allowed resolution of both cardiac and respiratory cycles employing rapid spiral acquisition [SPR-PC] were employed. Total arterial renal blood flow was calculated for each individual. Measurements of renal blood flow via standard techniques of PAH clearance-hematrocrit were obtained for each subject the same day as the MRI examinations. Results: The agreement between normal renal blood flow measurements for the PAH clearance techniques and the various Cine-PC techniques employing spiral acquisition was very good, with the SPR-PC technique giving the best agreement, when data in end expiration was analyzed. A two standard deviation range of agreement between this latter technique with the PAH clearance-hematocrit value was 115%. Conclusions: The Cine-PC techniques employing rapid spiral acquisitions appear capable of accurate in vivo measurement of human renal blood flow. The techniques give a good deal of promise for clinical measurement of renal blood flow which may be reduced in such conditions as renal artery stenosis.

引言：本研究的目的是评估 快速螺旋电影相位对比MRI技术的能力 采集以测量体内正常人肾血流。 十五 正常志愿者进行电影相位对比MRI研究。 研究方法： 采用快速螺旋采集的屏气技术[Spiral-PC]， 以及Cine-PC技术，该技术可以分辨心脏和 采用快速螺旋采集[SPR-PC]的呼吸周期 就业。 计算每例患者的总动脉肾血流量， 单独的. 通过标准技术测量肾血流量 的PAH清除率-红细胞压积， 当天进行MRI检查。 结果：正常对照组与正常对照组之间的一致性 PAH清除技术的肾血流量测量和 采用螺旋采集的各种Cine-PC技术非常好， SPR-PC技术给出了最好的协议，当数据结束时， 分析了过期时间。 两个标准差的一致性范围 后一种技术与PAH清除率-红细胞压积值之间 是115%。 结论：采用快速螺旋的Cine-PC技术 采集似乎能够准确地对人体进行体内测量 肾血流量 这些技术给了我们很大的希望， 在这种情况下可能减少的肾血流的临床测量 如肾动脉狭窄。