DIFFUSION WEIGHTED IMAGING OF COLD LESION TRAUMA IN RAT BRAIN

大鼠脑部冷损伤损伤的弥散加权成像

• 批准号: 6123014
• 负责人: CHRISTIAN BEAULIEU
• 金额: $ 1.75万
• 依托单位: STANFORD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-01-01 至 2000-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6123014
• 关键词: bioimaging /biomedical imaging; biomedical resource; magnetic resonance imaging; radiology; technology /technique

Introduction: The objective of this work was to design and utilize a flexible imaging sequence for ultra-fast, breath-held contrast-enhanced MR Angiography. Methods: Using the current generation of high speed imaging gradients it is possible to achieve sequence repetition times of 4 ms or less. This make it possible to obtain high resolution (512 x 512 x 64) images in under 30 seconds. The versatility of this technique will be demonstrated with applications including imaging of aortic dissection, thoracic and abdominal aortic aneurysm, pulmonary embolus, carotid stenosis, and peripheral vascular disease. We will discuss how the administration of contrast must be tailored to the vascular anatomy under examination to avoid venous enhancement. The rapid data acquisition times can be used to image multiple temporal phases or multiple spatial locations. Results/Conclusions: With this technique and the administration of a T1 shortening contrast agent, high quality MRA examinations can be routinely performed in a variety of vascular regions.

介绍：这项工作的目标是设计和 利用灵活的成像序列， 对比增强磁共振血管造影。 方法：使用当前 可以实现高速成像梯度的产生 序列重复时间为4 ms或更少。这使得有可能 在30秒内获得高分辨率（512 x 512 x 64）图像。 这种技术的多功能性将通过以下方式得到证明： 应用包括主动脉夹层、胸部和 腹主动脉瘤，肺栓塞，颈动脉狭窄， 外周血管疾病 我们将讨论政府如何 造影剂的剂量必须适合于检查中的血管解剖结构 以避免静脉强化 快速的数据采集时间可以 用于对多个时间相位或多个空间位置进行成像。 结果/结论：通过这种技术和管理， T1缩短对比剂，可进行高质量MRA检查 常规在各种血管区域进行。