CARCINOGENESIS, MOLECULAR AND CELLULAR BIOLOGY

这是11-15年的竞争性续期申请， 在致癌作用的分子和细胞生物学培训计划 俄亥俄州州立大学。 致癌作用培训计划旨在 培养博士前、博士后优秀人才 研究致癌作用的职业。 培训将提供3-5 年，重点是严格的，深入的培训，在致癌作用， 包括分子生物学、分子遗传学、生物化学 细胞生物学、药理学、神经肿瘤学、病理学等学科 在癌症研究中。 从申请者中选择受训人员 申请研究生和研究生培训将根据过去的 学术成就，学术潜力，明确的承诺， 在致癌作用的研究生涯，和高水平的科学诚信。 将尽一切努力从以下方面招聘和留住申请人： 代表性不足的种族和族裔群体。 博士预科候选人将 在成功完成2年的培训课程后， 当然，在一个与培训计划有关的部门工作。 培训计划所需的核心课程包括生物化学 致癌机制、肿瘤学基础和辐射 生物学 选修课程将根据具体的学术选择 和研究的需要。 所有学员必须 参加与分子生物学中心联合举办的每周一次的系列研讨会 环境卫生和放射生物学，并积极参与 致癌杂志俱乐部。 每一位学员的进步都将密切关注 然后是一个咨询委员会，他们将被鼓励提出 他们的研究成果在地方和国家会议，并发表他们的 在高质量的期刊上发表。 培训结束后 计划，博士前和博士后学员将高度 在学术机构、政府和 行业 参加培训计划的11位教师 在医学、药学、生物学学院内维持实验室 科学和兽医学，具有广泛的专业知识， 癌症研究领域，是富有成效的，并高度互动。 学员和教师可以开放访问广泛的最先进的核心 实验室的人 综合癌症中心，包括 转基因小鼠、肽合成、DNA测序、 寡核苷酸合成，质谱，共聚焦图像分析，细胞 分类和组织采购网络。 特别行动组保持着广泛 图书馆设施和俄亥俄州超级计算机中心的所在地， 提供互联网链接到校园周围的调查人员，以及其他 机构在国内和国际上。

This is the competitive renewal application for years 11-15 for the Training Program in Molecular and Cellular Biology of Carcinogenesis at the Ohio State University. The Carcinogenesis training program is designed to train outstanding scholars at both the predoctoral and postdoctoral levels for research careers in carcinogenesis. Training will be provided for 3-5 years, with emphasis on rigorous, in depth training in carcinogenesis which include disciplines of molecular biology, molecular genetics, biochemistry, cell biology, pharmacology, neurooncology, pathology, and other disciplines in cancer research. The choice of trainees from the applicant pool applying for graduate and post-graduate training will be based on past academic achievements, academic potential, unequivocal commitment to a research career in carcinogenesis, and high level of scientific integrity. Every effort will be made to recruit and retain applicants from underrepresented racial and ethnic groups. Predoctoral candidates will be admitted to the training program following successful completion of 2 years of course work in a Department affiliated with the training program. Required core courses for the training program include Biochemical Mechanisms of Carcinogenesis, Fundamentals of Oncology, and Radiation Biology. Elective courses will be selected based on the specific academic and research needs of the individual trainee. All trainees are required to attend a weekly seminar series held jointly with the Center for Molecular Environmental Health and Radiobiology and to actively participate in a Carcinogenesis journal club. The progress of each trainee will be closely followed by an advisory committee and they will be encouraged to present their research results at local and national meeting and to publish their findings in high quality journals. Following completion of the training program, the predoctoral and postdoctoral trainees will be highly competitive for positions in academic settings, in government, and industry. The 11 Faculty preceptors participating in the training program maintain laboratories within the Colleges of Medicine, Pharmacy, Biological Sciences, and Veterinary Medicine, have a broad range of expertise in the field of cancer research, are productive,a nd are highly interactive. Trainees and faculty have open access to extensive state-of-the-art core laboratories in the O.S.U. Comprehensive Cancer Center including facilities for transgenic mice, peptide synthesis, DNA sequencing, oligonucleotide synthesis, mass spectrometry, confocal image analysis, cell sorting, and a tissue procurement network. O.S.U. maintains extensive library facilities and its home to The Ohio Supercomputer Center, which provides Internet links to investigators around campus, and to other institutions nationally and internationally.