CARCINOGENESIS, MOLECULAR AND CELLULAR BIOLOGY
CARCINOGENESIS, MOLECULAR AND CELLULAR BIOLOGY
批准号:
6172128
负责人:
FREDIKA A ROBERTSON
金额:
$10.89万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
1984
资助国家:
美国
项目状态:
已结题
起止时间:
1984-09-01 至 2002-03-31
中文摘要
这是11-15年级的竞争性续期申请
英文摘要
This is the competitive renewal application for years 11-15 for the
Training Program in Molecular and Cellular Biology of Carcinogenesis at the
Ohio State University. The Carcinogenesis training program is designed to
train outstanding scholars at both the predoctoral and postdoctoral levels
for research careers in carcinogenesis. Training will be provided for 3-5
years, with emphasis on rigorous, in depth training in carcinogenesis which
include disciplines of molecular biology, molecular genetics, biochemistry,
cell biology, pharmacology, neurooncology, pathology, and other disciplines
in cancer research. The choice of trainees from the applicant pool
applying for graduate and post-graduate training will be based on past
academic achievements, academic potential, unequivocal commitment to a
research career in carcinogenesis, and high level of scientific integrity.
Every effort will be made to recruit and retain applicants from
underrepresented racial and ethnic groups. Predoctoral candidates will be
admitted to the training program following successful completion of 2 years
of course work in a Department affiliated with the training program.
Required core courses for the training program include Biochemical
Mechanisms of Carcinogenesis, Fundamentals of Oncology, and Radiation
Biology. Elective courses will be selected based on the specific academic
and research needs of the individual trainee. All trainees are required to
attend a weekly seminar series held jointly with the Center for Molecular
Environmental Health and Radiobiology and to actively participate in a
Carcinogenesis journal club. The progress of each trainee will be closely
followed by an advisory committee and they will be encouraged to present
their research results at local and national meeting and to publish their
findings in high quality journals. Following completion of the training
program, the predoctoral and postdoctoral trainees will be highly
competitive for positions in academic settings, in government, and
industry. The 11 Faculty preceptors participating in the training program
maintain laboratories within the Colleges of Medicine, Pharmacy, Biological
Sciences, and Veterinary Medicine, have a broad range of expertise in the
field of cancer research, are productive,a nd are highly interactive.
Trainees and faculty have open access to extensive state-of-the-art core
laboratories in the O.S.U. Comprehensive Cancer Center including
facilities for transgenic mice, peptide synthesis, DNA sequencing,
oligonucleotide synthesis, mass spectrometry, confocal image analysis, cell
sorting, and a tissue procurement network. O.S.U. maintains extensive
library facilities and its home to The Ohio Supercomputer Center, which
provides Internet links to investigators around campus, and to other
institutions nationally and internationally.
期刊论文(15)
专著(0)
科研奖励(0)
会议论文
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Polyadenylylation signal of the mouse thymidylate synthase gene was created by insertion of an L1 repetitive element downstream of the open reading frame.
小鼠胸苷酸合酶基因的多腺苷酸化信号是通过在开放阅读框下游插入 L1 重复元件而产生的。
DOI:
10.1073/pnas.87.7.2531
发表时间:
1990
期刊:
Proceedings of the National Academy of Sciences of the United States of America
影响因子:
11.1
作者:
[Harendza,CJ, Johnson,LF]
通讯作者:
Johnson,LF
Predilection of a nasopharyngeal carcinoma-derived isolate of Epstein-Barr virus for infection of specific subsets of B lymphocytes.
鼻咽癌衍生的 Epstein-Barr 病毒分离株倾向于感染特定的 B 淋巴细胞亚群。
DOI:
10.1002/jmv.1890290109
发表时间:
1989
期刊:
Journal of medical virology
影响因子:
12.7
作者:
[Tarr,KL, Glaser,R]
通讯作者:
Glaser,R
Chemopreventive activities of C-glucuronide/glycoside analogs of retinoid-O-glucuronides against breast cancer development and growth.
C-葡萄糖醛酸苷/类维生素A-O-葡萄糖苷酸苷类似物对乳腺癌发生和生长的化学预防活性。
DOI:
--
发表时间:
1996
期刊:
Anticancer research.
影响因子:
--
作者:
[CurleyJr,RW, Abou-Issa,H, Panigot,MJ, Repa,JJ, Clagett-Dame,M, Alshafie,G]
通讯作者:
Alshafie,G
Cocarcinogenicity of saccharin and N-alkylnitrosoureas in cultured human diploid fibroblasts.
糖精和 N-烷基亚硝基脲在培养的人二倍体成纤维细胞中的共同致癌性。
DOI:
10.1080/15287398809531171
发表时间:
1988
期刊:
Journal of toxicology and environmental health
影响因子:
--
作者:
[Milo,GE, Oldham,JW, Noyes,I, Lehman,TA, Kumari,L, West,RW, Kadlubar,FF]
通讯作者:
Kadlubar,FF
Inactivation of MED-1 elements in the TATA-less, initiator-less mouse thymidylate synthase promoter has no effect on promoter strength or the complex pattern of transcriptional start sites.
无 TATA、无起始子的小鼠胸苷酸合酶启动子中 MED-1 元件的失活对启动子强度或转录起始位点的复杂模式没有影响。
DOI:
10.1002/(sici)1097-4644(19990401)73:1
发表时间:
1999
期刊:
Journal of cellular biochemistry
影响因子:
4
作者:
[Rudge,TL, Johnson,LF]
通讯作者:
Johnson,LF
共 9 条
NITRIC OXIDE AND TUMOR PROMOTION
-
批准号:2462954
-
项目类别:
-
资助金额:$25.83万
-
财政年份:1997
-
负责人:FREDIKA A ROBERTSON
-
依托单位:
GENE SPECIFIC MUTATIONS IN SKIN INDUCED BY PEROXYNITRITE
-
批准号:6172945
-
项目类别:
-
资助金额:$28.99万
-
财政年份:1997
-
负责人:FREDIKA A ROBERTSON
-
依托单位:
GENE SPECIFIC MUTATIONS IN SKIN INDUCED BY PEROXYNITRITE
-
批准号:6376215
-
项目类别:
-
资助金额:$29.67万
-
财政年份:1997
-
负责人:FREDIKA A ROBERTSON
-
依托单位:
INFLAMMATION AND MULTISTAGE CARCINOGENESIS
-
批准号:2733319
-
项目类别:
-
资助金额:$28.09万
-
财政年份:1997
-
负责人:FREDIKA A ROBERTSON
-
依托单位:
NITRIC OXIDE AND TUMOR PROMOTION
-
批准号:2837792
-
项目类别:
-
资助金额:$26.61万
-
财政年份:1997
-
负责人:FREDIKA A ROBERTSON
-
依托单位:
GENE SPECIFIC MUTATIONS IN SKIN INDUCED BY PEROXYNITRITE
-
批准号:2683636
-
项目类别:
-
资助金额:$25.64万
-
财政年份:1997
-
负责人:FREDIKA A ROBERTSON
-
依托单位:
NITRIC OXIDE AND TUMOR PROMOTION
-
批准号:6124460
-
项目类别:
-
资助金额:$27.41万
-
财政年份:1997
-
负责人:FREDIKA A ROBERTSON
-
依托单位:
INFLAMMATION AND MULTISTAGE CARCINOGENESIS
-
批准号:6172864
-
项目类别:
-
资助金额:$35.48万
-
财政年份:1997
-
负责人:FREDIKA A ROBERTSON
-
依托单位:
INFLAMMATION AND MULTISTAGE CARCINOGENESIS
-
批准号:2405128
-
项目类别:
-
资助金额:$27.9万
-
财政年份:1997
-
负责人:FREDIKA A ROBERTSON
-
依托单位:
INFLAMMATION AND MULTISTAGE CARCINOGENESIS
-
批准号:2895808
-
项目类别:
-
资助金额:$33.61万
-
财政年份:1997
-
负责人:FREDIKA A ROBERTSON
-
依托单位:
GENE SPECIFIC MUTATIONS IN SKIN INDUCED BY PEROXYNITRITE
-
批准号:2895481
-
项目类别:
-
资助金额:$26.21万
-
财政年份:1997
-
负责人:FREDIKA A ROBERTSON
-
依托单位:
GENE SPECIFIC MUTATIONS IN SKIN INDUCED BY PEROXYNITRITE
-
批准号:2009403
-
项目类别:
-
资助金额:$26.48万
-
财政年份:1997
-
负责人:FREDIKA A ROBERTSON
-
依托单位:
CELLULAR BASIS FOR SILICONE-INDUCED IMMUNE RESPONSES
-
批准号:2069786
-
项目类别:
-
资助金额:$13.41万
-
财政年份:1993
-
负责人:FREDIKA A ROBERTSON
-
依托单位:
CELLULAR BASIS FOR SILICONE-INDUCED IMMUNE RESPONSES
-
批准号:3149511
-
项目类别:
-
资助金额:$13.88万
-
财政年份:1993
-
负责人:FREDIKA A ROBERTSON
-
依托单位:
CELLULAR BASIS FOR SILICONE-INDUCED IMMUNE RESPONSES
-
批准号:2069785
-
项目类别:
-
资助金额:$12.9万
-
财政年份:1993
-
负责人:FREDIKA A ROBERTSON
-
依托单位:
ROLE OF ADHESION MOLECULES/CYTOKINES IN TUMOR PROMOTION
-
批准号:3199676
-
项目类别:
-
资助金额:$14.25万
-
财政年份:1991
-
负责人:FREDIKA A ROBERTSON
-
依托单位:
ROLE OF ADHESION MOLECULES & CYTOKINES IN TUMOR PROMOTIO
-
批准号:3199675
-
项目类别:
-
资助金额:$0.97万
-
财政年份:1991
-
负责人:FREDIKA A ROBERTSON
-
依托单位:
ROLE OF ADHESION MOLECULES & CYTOKINES IN TUMOR PROMOTIO
-
批准号:3199677
-
项目类别:
-
资助金额:$14.82万
-
财政年份:1991
-
负责人:FREDIKA A ROBERTSON
-
依托单位:
ROLE OF ADHESION MOLECULES & CYTOKINES IN TUMOR PROMOTIO
-
批准号:3199678
-
项目类别:
-
资助金额:$13.71万
-
财政年份:1991
-
负责人:FREDIKA A ROBERTSON
-
依托单位:
ROLE OF KERATINOCYTE SUB-POPULATIONS IN TUMOR PROMOTION
-
批准号:3196176
-
项目类别:
-
资助金额:$20.69万
-
财政年份:1990
-
负责人:FREDIKA A ROBERTSON
-
依托单位:
国内基金
海外基金
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Kidney injury molecular(KIM-1)介导肾小管上皮细胞自噬在糖尿病肾病肾间质纤维化中的作用
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批准号:81300605
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项目类别:青年科学基金项目
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资助金额:23.0万元
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批准年份:2013
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负责人:唐琳
-
依托单位:
Molecular Plant
-
批准号:31224801
-
项目类别:专项基金项目
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资助金额:20.0万元
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批准年份:2012
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负责人:黄健秋
-
依托单位:
Molecular Interaction Reconstruction of Rheumatoid Arthritis Therapies Using Clinical Data
-
批准号:31070748
-
项目类别:面上项目
-
资助金额:34.0万元
-
批准年份:2010
-
负责人:Christine Nardini
-
依托单位:
Molecular Plant
-
批准号:31024802
-
项目类别:专项基金项目
-
资助金额:20.0万元
-
批准年份:2010
-
负责人:陈晓亚
-
依托单位:
Cellular & Molecular Immunology
-
批准号:30824806
-
项目类别:专项基金项目
-
资助金额:20.0万元
-
批准年份:2008
-
负责人:魏海明
-
依托单位: