课题基金 / 基金详情

Development and refinement of neural connections in the adult brain in health and disease

Development and refinement of neural connections in the adult brain in health and disease
健康和疾病中成人大脑神经连接的发展和完善
批准号:
nhmrc : 569575
负责人:
Prof Pankaj Sah
金额:
$537.55万
依托单位国家:
澳大利亚
项目类别:
Programs
财政年份:
2009
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2009-01-01 至 2013-12-31

项目摘要

项目成果

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中文摘要
翻译
我们的团队将使用先进的成像和细胞分选等创新方法以及动物模型的开发来确定新神经元是如何生成的,它们如何到达大脑的不同部分,以及它们如何整合到现有的大脑电路中。这些发现将为治疗衰老和病理期间的脑损伤提供新的方法。由于团队成员以前曾参与将分子发现进展到临床试验,我们也处于与生物制药行业合作开发这些发现的有利地位。
英文摘要
Our group will use innovative approaches such as advanced imaging and cell-sorting and development of animal models to determine how new neurons are generated, how they travel to different parts of the brain and how they integrate into the existing brain circuitry. These discoveries will point to new ways in which to treat brain damage both during ageing and during pathology. Since team members have previously been involved in progressing molecular discovery to clinical trials, we are also in a good position to exploit these discoveries in partnership with the biopharmaceutical industry.
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会议论文
Network activity and the role of NMDA receptors in associative learning
  • 批准号:
    DP220102377
  • 项目类别:
    Discovery Projects
  • 资助金额:
    $54.96万
  • 财政年份:
    2022
  • 负责人:
    Prof Pankaj Sah
  • 依托单位:
Brain connectome: from synapse, large-scale network to behaviour
  • 批准号:
    DP180103319
  • 项目类别:
    Discovery Projects
  • 资助金额:
    $25.23万
  • 财政年份:
    2018
  • 负责人:
    Prof Pankaj Sah
  • 依托单位:
Neural circuits that mediate fear extinction
  • 批准号:
    nhmrc : 1128427
  • 项目类别:
    Project Grants
  • 资助金额:
    $64.34万
  • 财政年份:
    2017
  • 负责人:
    Prof Pankaj Sah
  • 依托单位:
Neural circuits that mediate fear extinction
  • 批准号:
    nhmrc : GNT1128427
  • 项目类别:
    Project Grants
  • 资助金额:
    $94.17万
  • 财政年份:
    2017
  • 负责人:
    Prof Pankaj Sah
  • 依托单位:
海外基金