Examination of emotion regulation strategy use in an outpatient treatment program for adolescents with co-occurring disorders

情绪调节策略在青少年并发疾病门诊治疗计划中的应用研究

• 批准号: 10723521
• 负责人: Tiffany Jenzer
• 金额: $ 13.41万
• 依托单位: EMMA PENDLETON BRADLEY HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-15 至 2025-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10723521
• 关键词: Address; Adolescence; Adolescent; Adult; Alcohol consumption; Ambulatory Care; Anxiety; Area; Attention deficit hyperactivity disorder; Behavior; Communities; Comprehension; Data; Development; Diagnosis; Diagnostic; Dialectical behavior therapy; Disease; Ecological momentary assessment; Emotional; Enrollment; Exhibits; Feedback; Goals; Grant; Growth; Intervention; Learning Skill; Mental Depression; Mental disorders; Mentors; Methods; National Institute on Alcohol Abuse and Alcoholism; Nature; Participant; Patient Self-Report; Phase; Pilot Projects; Population; Population Intervention; Procedures; Process; Protocols documentation; Psychiatric Diagnosis; Psychopathology; Reporting; Research; Research Personnel; Resources; Role; Sampling; Scientist; Strategic Planning; Symptoms; Testing; Training; Treatment outcome; Work; Youth; acceptability and feasibility; adolescent alcohol treatment; adolescents with alcohol use disorders; aged; alcohol abuse therapy; alcohol craving; alcohol use disorder; associated symptom; cost; dual diagnosis; effective intervention; emotion dysregulation; emotion regulation; executive function; experience; feasibility testing; improved; outpatient programs; participant enrollment; prospective; randomized, clinical trials; satisfaction; skill acquisition; skills; skills training; treatment program; underage drinking

PROJECT SUMMARY/ABSTRACT Most adolescents (61-88%) who present to treatment with alcohol use disorder (AUD) have a co-occurring psychiatric diagnosis. Youth with AUD and a co-occurring diagnosis exhibit poorer general functioning and worse treatment outcomes compared to those with AUD alone. Unfortunately, treatments for adolescent AUD lag behind those for adults and show small effect sizes. To improve interventions for this population, there is a need to understand how and why adolescent AUD treatments work and to identify transdiagnostic treatment mechanisms that can target symptoms of multiple disorders simultaneously. Emotion regulation skill use is one such mechanism. This proposal leverages ecological momentary assessment (EMA) to study the change in emotion regulation skill use within a treatment context as well as examine its influence on relevant AUD and co-occurring disorder treatment outcomes. The proposed research will examine these processes within a community sample of adolescents (aged 13-18) undergoing an intensive outpatient program for AUD and co- occurring disorders. Given the cost and labor-intensive resources required for EMA research and the little work using EMA with this population, the K99 project will consist of a pilot study to test the feasibility and acceptability of the EMA protocol, will identify barriers to compliance, and will refine the protocol. (Aims 1a-1c). The R00 project (N = 80 adolescents) will consist of a 10-week study during which participants will complete two 3-week bursts of EMA reports. Aims of the R00 project are to examine prospective momentary associations between emotion regulation skill use and momentary treatment outcomes (Aim 2), to characterize the extent of change in emotion regulation skill use across treatment (Aim 3a) and examine whether changes in emotion regulation skill use coincide with changes in treatment outcomes across treatment (Aim 3b). Findings will serve as pilot data to a larger NIAAA R01 grant submission in this area of work. Importantly, this K99/R00 application will serve as foundational training for Dr. Jenzer's development as an independent scientist. Mentors (Drs. Miranda, Magill, Weiss, Litt) are committed to the candidate's training and each will provide unique expertise to the research and training plan.

项目摘要/摘要 大多数接受酒精使用障碍（AUD）治疗的青少年（61-88%）有一个共同发生的 精神病诊断患有AUD和合并诊断的青少年表现出较差的一般功能， 与单独使用AUD的患者相比，治疗结局更差。不幸的是，青少年AUD的治疗 滞后于成人，并显示出小的效应量。为了改善对这一人群的干预， 需要了解青少年AUD治疗如何以及为什么起作用，并确定跨诊断治疗 这些机制可以同时针对多种疾病的症状。情绪调节技巧的使用是一种 这样的机制。该提案利用生态瞬时评估（EMA）来研究 在治疗背景下使用情绪调节技能，并检查其对相关AUD和 共病治疗结果。拟议的研究将在一个范围内检查这些过程 社区样本青少年（13-18岁）接受强化门诊计划AUD和co， 发生紊乱。考虑到EMA研究所需的成本和劳动密集型资源， K99项目将包括一项试验性研究，以测试该项目的可行性， EMA方案的可接受性，将识别依从性障碍，并将完善方案。(Aims 1a-1c）。 R 00项目（N = 80名青少年）将包括一项为期10周的研究，在此期间，参与者将完成 连续两周的EMA报告。R 00项目的目的是检查未来的瞬时 情绪调节技能的使用和瞬时治疗结果之间的关联（目的2），以表征 在治疗过程中使用情绪调节技能的变化程度（目标3a），并检查是否变化 情绪调节技能的使用与治疗结果的变化一致（目标3b）。 调查结果将作为试点数据，以更大的NIAAA R 01赠款提交在这一领域的工作。重要的是这 K99/R 00应用程序将作为Jenzer博士作为独立开发人员的基础培训 科学家导师（米兰达博士、马吉尔博士、韦斯博士、利特博士）致力于候选人的培训， 为研究和培训计划提供独特的专业知识。