FASEB CONFERENCE/MOLECULAR BIOPHYSICS OF MEMBRANES

描述：(逐字摘自申请者的摘要)建议的FASEB夏季 题为“细胞膜的分子生物物理学”的会议将于 2000年7月15日至20日，在佛蒙特州萨克斯顿河的佛蒙特州学院举行。与 基因组数据库中序列信息的积累，已经成为 显然，大量的基因都致力于基因的规范 膜蛋白。此外，膜蛋白及其脂质环境具有 更慢地屈服于结构生物学、生物化学和 生物物理学，考虑到溶解性、稳定性和提纯的困难 对于这些分子物种来说，强调了新方法的必要性 和想法。在这次会议上，运用来自 讨论了膜生物学中的生物物理化学问题。一些 会议对这一主题的探讨比以往任何时候都要深入和严谨 这是过去的会议，计划在下一次迭代中进行。 通过提供一个深入讨论这一主题基本思想的场所 地区，为青年科学家进入的教育创造了环境 在这一领域，以及更资深人士的思维发展方面也是如此。 重点将放在使用量化方法来确定 对结构和机制的理解。人们认为……的发展 详细的分析是发展的最重要的途径 概括生物学这一重要领域的思想。

DESCRIPTION: (Verbatim from the Applicant's Abstract) The proposed FASEB summer meeting entitled "Molecular Biophysics of Cellular Membranes" will be held on July 15-20, 2000 at the Vermont Academy in Saxton's River, Vermont. With the accumulation of sequence information in genomic databases, it has become apparent that a very large number of genes are devoted to the specification of membrane proteins. Further, membrane proteins and their lipid environment have yielded more slowly to the efforts of structural biology, biochemistry, and biophysics, given the difficulties of solubility, stability, and purification that arise for these molecular species, emphasizing the need for new approaches and ideas. In this conference, the important subject of applying ideas from biophysical chemistry to problems in membrane biology is addressed. Few meetings approach the subject with the depth and rigor than has characterized this meeting in the past and that is planned for the next iteration. By providing a venue for a deep treatment of fundamental ideas in this subject area, an environment is created for the education of young scientists entering the field, as well as for the development of thinking by more senior figures. An emphasis will be placed on the use of quantitative approaches to an understanding of structure and mechanism. It is felt that the development of detailed analysis is the most important pathway to the development of generalizing ideas in this important field of biology.