NNFF CONSORTIUM:MOLECULAR AND CELL BIOLOGY OF NF1& NF2

NNFF 联盟：NF1 的分子和细胞生物学

• 批准号: 6165831
• 负责人: KEVIN M. SHANNON
• 金额: $ 2.3万
• 依托单位: CHILDREN'S TUMOR FOUNDATION
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-05-24 至 2001-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6165831
• 关键词: cell biology; meeting /conference /symposium; molecular biology; neurofibromatosis; travel

Funding is requested to support the next meeting of the National Neurofibromatosis Foundation International Consortium for the Molecular and Cell Biology of NF1 and NF2 to be held June 4-7, 2000 at the Hotel Jerome in Aspen, Colorado. Beginning with the first meeting in 1985, these conferences have served as the catalysts for many of the fundamental discoveries that have contributed major insights into these important diseases of the nervous system. These meetings provide a regular forum to bring together basic researchers, geneticists, clinicians, and others familiar with NF1 and NF2 to share their latest research findings and experiences. NNFF Consortia have been instrumental in the rapid advances in the molecular understanding of NF1 and NF2, including the cloning of the responsible genes, establishment of diagnostic tests, exploration of protein function, development of animal models, and creation of a network of patients and clinicians to facilitate clinical trials. The 2000 Consortium meeting has been organized as an open meeting that will be advertised to the general scientific community. Each of six platform sessions will be chaired by an expert in the field. These sessions will include 2 invited speakers from the NF research community with the other presentations to be selected from submitted abstracts. Participation by junior investigators will be encouraged and the organizers anticipate, on basis of previous Consortium meetings, that a substantial percentage of the speakers will be young investigators. Speakers will be instructed to limit their presentations to approximately half of the allotted time, with the remainder dedicated to open discussion among all participants. In addition, longer talks by four keynote speakers who are leaders in scientific fields or emerging technologies that are directly relevant to NF research will be incorporated into some of the scientific sessions. Two poster sessions will also be held which will allow investigators to present abstracts that are not selected for one of the oral sessions. In addition to updating investigators working on NF1 and NF2 on the latest research developments, this meeting will help to identify critical gaps in our knowledge as well as strategies and collaborations to address them. An improved understanding of the molecular basis of NF1 and NF2 will play an essential role in developing improved therapies for the complications of these disorders and has broad implications to the fields of developmental neurobiology and cancer research.

要求资助支持NF1和NF2的分子和细胞生物学国际国家神经瘤病基金会的下次会议，2000年6月4日至7日在科罗拉多州阿斯彭的Jerome Hotel Jerome举行。从1985年的第一次会议开始，这些会议是许多基本发现的催化剂，这些发现对神经系统的这些重要疾病有了重大见解。这些会议提供了一个常规的论坛，将基础研究人员，遗传学家，临床医生以及其他熟悉NF1和NF2的人汇总在一起，以分享他们最新的研究结果和经验。 NNFF联盟对NF1和NF2的分子理解的快速进步发挥了作用，包括克隆负责的基因，建立诊断测试，探索蛋白质功能，动物模型的发展以及创建患者和临床医生网络，以促进临床试验。 2000年的财团会议已被组织为公开会议，该会议将为一般科学界做广告。六个平台会议中的每一个都将由该领域的专家主持。这些会议将包括来自NF研究社区的2位受邀演讲者，并从提交的摘要中选择其他演讲。将鼓励初级调查人员的参与，组织者预计，根据先前的财团会议，很大一部分的演讲者将是年轻的调查员。演讲者将被指示将其演示文稿限制为大约一半的分配时间，其余的专门用于所有参与者之间的讨论。此外，四位主题演讲者的会谈较长，他们是科学领域的领导者或与NF研究直接相关的新兴技术的领导者，将纳入一些科学会议中。还将举行两次海报会议，这将使研究人员能够提出未在其中一个课程中选择的摘要。除了更新从事NF1和NF2的调查人员有关最新研究开发的研究人员之外，这次会议还将有助于确定我们知识的关键差距，以及解决方案的策略和协作。对NF1和NF2的分子基础的改进理解将在开发这些疾病并发症的改善疗法方面起着至关重要的作用，并对发育神经生物学和癌症研究领域具有广泛的影响。