Career Development Program

职业发展计划

• 批准号: 8932167
• 负责人: KEVIN M. SHANNON
• 金额: $ 10.45万
• 依托单位: INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-09-01 至 2020-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8932167
• 关键词: Address; Area; Basic Science; Budgets; California; Cancer Biology; Childhood; Cities; Clinical; Clinical Sciences; Data; Development; Development Plans; Disadvantaged; Discipline; Extramural Activities; Faculty; Funding; Goals; Human; Indiana; Individual; Institution; Knowledge; Lesbian Gay Bisexual; Link; Malignant Neoplasms; Medical center; Mentors; Mission; Mutation; NF1 gene; National Cancer Institute; Nature; North Carolina; Pediatric Hospitals; Pennsylvania; Philadelphia; Population; Process; Recruitment Activity; Reproduction spores; Research; Research Personnel; Research Project Grants; Resources; San Francisco; Schedule; Scientist; Signal Transduction; Structure; Texas; Textiles; Therapeutic; Training; Translational Research; Underrepresented Minority; Universities; Woman; Work; abstracting; anticancer research; cancer therapy; career; career development; ethnic minority population; innovation; meetings; member; professor; programs; skills; success; transgender; tumor

ABSTRACT – CAREER DEVELOPMENT PROGRAM The Developmental Hyperactive Ras Tumor (DHART) SPORE Career Development Program (CDP) will support faculty at the Assistant Professor level to engage in translational research focused on NF1 and cancer. The specific purpose or the CDP is to advance the careers of junior investigators who are developing innovative research projects related to the goal of implementing more effective and less toxic therapies for cancers characterized by NF1 mutations. The DHART SPORE also includes a Developmental Research Program (DRP), which has the complementary mission of funding established investigators who seek to develop new research related to NF1-related cancers and is presented in a separate section of this application. The multi-institutional nature of this SPORE leverages a large and talented pool of junior faculty from multiple disciplines. Each institution views the CDP as a vehicle for recruiting, training, and advancing young scientists working in the area of translational cancer research related to NF1, and they have committed $1.3 million to support the Developmental Programs component of the DHART SPORE (DRP and CDP). The Specific Aims of the CDP are: (1) to support new investigators as they develop innovative research programs with the goal of contributing new knowledge to the field of NF1-related cancer research while generating preliminary data that will allow them to successfully apply for independent extramural funding; (2) to provide young researchers with didactic training that will equip them with essential skills and knowledge for success as an independent investigator in the field of NF1-related cancer research; (3) to mentor young translational researchers through regularly scheduled one-on-one meetings with a designated senior faculty member and a structured Individual Career Development Plan (IDP) who will fully integrate the CDP-supported investigator into the fabric of the DHART SPORE where they have access to advice, resources, and potential collaborators; and, (4) to encourage the recruitment of ethnic minorities, those from disadvantaged backgrounds, women and lesbian/gay/bisexual/transgender (LGBT) populations into research focused on NF1-associated cancers. The DHART SPORE will link vertically and horizontally to diversity programs at all of the consortium institutions. Investigators from any of these centers can apply for CDP funds, and we will also consider proposals from researchers at other institutions. The CDP will fund a minimum of two projects per year at an annual budget of $50,000 - $75,000. Applications for CDP support (including requests for a second year of funding) will be evaluated through a competitive process with review by a Developmental Programs Steering Committee comprised on senor scientists participating in this SPORE and oversight and guidance from the External and Internal Advisory Boards.

摘要 - 职业发展计划 发育多动Ras肿瘤（DHART）孢子职业发展计划（CDP）将 助理教授级别的支持教师从事以NF1和癌症为重点的翻译研究。 具体目的或CDP是促进正在发展的初级调查人员的职业 与实施更有效且毒性较小的疗法有关的创新研究项目 以NF1突变为特征的癌症。 Dhart孢子还包括一项发展研究 计划（DRP），其具有资金的完整任务，他们试图 开发与NF1相关癌症有关的新研究，并在本应用程序的单独部分中介绍。 该孢子的多机构性质利用了多个教师的大量少年教师 学科。每个机构都将CDP视为招募，培训和推进年轻科学家的工具 在与NF1有关的翻译癌症研究领域的工作，他们承诺了130万美元 支持Dhart Spore（DRP和CDP）的发展程序组件。具体目标 CDP的是：（1）支持新调查人员开发创新的研究计划，目的是 为NF1相关癌症研究领域贡献新知识，同时产生初步数据 将使他们能够成功申请独立的壁外资金； （2）为年轻研究人员提供 教学培训将使他们具备基本技能和知识，以获得独立的成功 NF1相关癌症研究领域的研究人员； （3）通过心理年轻人翻译研究人员 通常计划与指定的高级教师和一个结构化的个人进行一对一的会议 职业发展计划（IDP）将完全整合CDP支持的研究者 Dhart Spore可以使用建议，资源和潜在合作者；和，（4）to 鼓励招募少数民族，来自处境不利的背景，妇女和 女同性恋/同性恋/双性恋/变性者（LGBT）人群集中于与NF1相关的癌症。这 Dhart Spore将垂直和水平与所有联盟机构的多样性计划联系起来。 这些中心的调查人员可以申请CDP资金，我们还将考虑 其他机构的研究人员。 CDP每年至少为两个项目提供年度预算 $ 50,000- $ 75,000。 CDP支​​持的申请（包括第二年的资金请求）将是 通过开发计划指导委员会审查的竞争过程进行评估 包括参与此孢子的科学家，外部的监督以及指导 内部咨询委员会。