Career Development Program

职业发展计划

• 批准号: 8932167
• 负责人: KEVIN M. SHANNON
• 金额: $ 10.45万
• 依托单位: INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-09-01 至 2020-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8932167
• 关键词: Address; Area; Basic Science; Budgets; California; Cancer Biology; Childhood; Cities; Clinical; Clinical Sciences; Data; Development; Development Plans; Disadvantaged; Discipline; Extramural Activities; Faculty; Funding; Goals; Human; Indiana; Individual; Institution; Knowledge; Lesbian Gay Bisexual; Link; Malignant Neoplasms; Medical center; Mentors; Mission; Mutation; NF1 gene; National Cancer Institute; Nature; North Carolina; Pediatric Hospitals; Pennsylvania; Philadelphia; Population; Process; Recruitment Activity; Reproduction spores; Research; Research Personnel; Research Project Grants; Resources; San Francisco; Schedule; Scientist; Signal Transduction; Structure; Texas; Textiles; Therapeutic; Training; Translational Research; Underrepresented Minority; Universities; Woman; Work; abstracting; anticancer research; cancer therapy; career; career development; ethnic minority population; innovation; meetings; member; professor; programs; skills; success; transgender; tumor

ABSTRACT – CAREER DEVELOPMENT PROGRAM The Developmental Hyperactive Ras Tumor (DHART) SPORE Career Development Program (CDP) will support faculty at the Assistant Professor level to engage in translational research focused on NF1 and cancer. The specific purpose or the CDP is to advance the careers of junior investigators who are developing innovative research projects related to the goal of implementing more effective and less toxic therapies for cancers characterized by NF1 mutations. The DHART SPORE also includes a Developmental Research Program (DRP), which has the complementary mission of funding established investigators who seek to develop new research related to NF1-related cancers and is presented in a separate section of this application. The multi-institutional nature of this SPORE leverages a large and talented pool of junior faculty from multiple disciplines. Each institution views the CDP as a vehicle for recruiting, training, and advancing young scientists working in the area of translational cancer research related to NF1, and they have committed $1.3 million to support the Developmental Programs component of the DHART SPORE (DRP and CDP). The Specific Aims of the CDP are: (1) to support new investigators as they develop innovative research programs with the goal of contributing new knowledge to the field of NF1-related cancer research while generating preliminary data that will allow them to successfully apply for independent extramural funding; (2) to provide young researchers with didactic training that will equip them with essential skills and knowledge for success as an independent investigator in the field of NF1-related cancer research; (3) to mentor young translational researchers through regularly scheduled one-on-one meetings with a designated senior faculty member and a structured Individual Career Development Plan (IDP) who will fully integrate the CDP-supported investigator into the fabric of the DHART SPORE where they have access to advice, resources, and potential collaborators; and, (4) to encourage the recruitment of ethnic minorities, those from disadvantaged backgrounds, women and lesbian/gay/bisexual/transgender (LGBT) populations into research focused on NF1-associated cancers. The DHART SPORE will link vertically and horizontally to diversity programs at all of the consortium institutions. Investigators from any of these centers can apply for CDP funds, and we will also consider proposals from researchers at other institutions. The CDP will fund a minimum of two projects per year at an annual budget of $50,000 - $75,000. Applications for CDP support (including requests for a second year of funding) will be evaluated through a competitive process with review by a Developmental Programs Steering Committee comprised on senor scientists participating in this SPORE and oversight and guidance from the External and Internal Advisory Boards.

摘要-职业发展 发展性过度活跃Ras肿瘤（DHART）SPORE职业发展计划（CDP）将 支持助理教授级别的教师从事以NF 1和癌症为重点的转化研究。 CDP的具体目的是促进正在发展的初级调查员的职业生涯 与实施更有效和毒性更小的治疗目标有关的创新研究项目， 以NF 1突变为特征的癌症。DHART孢子还包括一项发展研究， 该计划（DRP）的补充使命是为寻求 开发与NF 1相关的癌症相关的新研究，并在本申请的单独部分中提出。 这个SPORE的多机构性质利用了来自多个国家的大量有才华的初级教师 学科每个机构都将CDP视为招募、培训和培养年轻科学家的工具 致力于与NF 1相关的转化癌症研究领域，他们承诺投入130万美元， 支持DHART SPORE的发展计划部分（DRP和CDP）。具体目标 CDP的目标是：（1）支持新的研究人员开发创新的研究计划， 为NF 1相关癌症研究领域贡献新知识，同时生成初步数据， 将使他们能够成功申请独立的校外资助;（2）为年轻的研究人员提供 教学培训，将使他们具备作为独立工作者取得成功的基本技能和知识 NF 1相关癌症研究领域的研究者;（3）通过以下方式指导年轻的翻译研究人员 定期安排与指定的高级教师和结构化的个人一对一的会议 职业发展计划（IDP），该计划将把CDP支持的调查员完全融入 DHART SPORE，他们可以获得建议，资源和潜在的合作者;以及，（4） 鼓励招聘少数族裔、来自弱势背景的人、妇女和 女同性恋/男同性恋/双性恋/跨性别（LGBT）人群的研究集中在NF 1相关的癌症。的 DHART SPORE将垂直和水平地与所有联盟机构的多样性计划联系起来。 来自任何这些中心的调查人员都可以申请CDP基金，我们也将考虑来自 其他机构的研究人员。CDP每年至少资助两个项目，年度预算为 五万到七万五CDP支持申请（包括第二年资助申请）将在 通过竞争过程进行评估，并由发展计划指导委员会进行审查 包括参与该SPORE的高级科学家以及外部和 内部咨询委员会。