TRAINING IN CARTILAGE RESEARCH

软骨研究培训

• 批准号: 6171568
• 负责人: KLAUS E KUETTNER
• 金额: $ 14.66万
• 依托单位: RUSH UNIVERSITY MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 1996
• 资助国家: 美国
• 起止时间: 1996-05-01 至 2001-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6171568
• 关键词: TRAINING; CARTILAGE; RESEARCH

This revised application for a training grant outlines the educational and training facilities in the Department of Biochemistry. Through its close interaction with members of the Department of Orthopaedic Surgery and the Section of Rheumatology and the renewal of the sole NIH-SCOR grant in osteoarthritis, a significant segment of the faculty is dedicated to basic researching the field of connective tissue and cartilage biochemistry, as it relates to arthritic conditions, especially osteoarthritis (OA). This has led to a major commitment to training predoctorate (Ph.D.) candidates and postdoctorate fellows, who carry out under the guidance of a faculty member research in this and other medically relevant areas. In the rebuttal to the review of the original application, it is pointed out that the Ph.D. training program combines a standard regimen of coursework in basic biochemistry with emphasis on medical relevance, as well as specialized courses in connective tissue (cartilage) biochemistry. Since the initiation of the Ph.D. program in 1984, 26 candidates have received their Ph.D. degrees; 12 of them presented their dissertation in the field of connective tissue (cartilage) biochemistry. The current 26 Ph.D. students actively participate in weekly departmental workshops and interact with nationally and internationally recognized experts in cartilage research, who are invited bi-monthly to the Department. (8 of them have not chosen their advisors yet; among the remaining, 14 have selected a Ph.D.-advisor from the faculty involved in connective tissue/cartilage research). Through this redrafted application, financial support is sought for three students per year for 5 years (equal 43 student-years). The training program for postdoctorate fellows has a select focus on cartilage biochemistry and osteoarthritis based on an assignment by the World Health Organization. It has provided training for 44 postdoctorate fellows from around the globe. Currently 10 fellows are working in the Department (about 50% of past or current fellows hold the M.D. degree). Each postdoctorate fellow is assigned to a faculty member, but broader education is facilitated through the weekly workshops, formal seminars, interactive discussions with visiting scientists and informal discussion groups. The postdoctorate training program enables the fellows to become active members of an investigative team, to learn the design of individual research strategies, to expand their professional goals, to monitor and teach graduate and medical school classes and to develop their writing skills from publications and grants. It allows them, as they enter the scientific work force, to make meaningful contributions to cartilage biochemistry. For the next five years, financial support is sought to pay for two postdoctorate fellowships per year (equal 10 fellowship-years). This training program is unique in preparing, side by side, graduate students and postdoctorate fellows for research careers. This new NIH Training Grant will enable the training program to focus on musculoskeletal investigations, especially cartilage biochemistry and the etiopathology of OA.

这份修订后的培训补助金申请表概述了教育和 生物化学系的培训设施。 保持紧密的 与矫形外科和 部分流变学和更新的唯一NIH-SCOR赠款在 骨关节炎，教师的一个重要部分是致力于基础 研究结缔组织和软骨生物化学领域， 它涉及关节炎病症，特别是骨关节炎（OA）。 这 导致了培养博士预科（博士）的重大承诺。候选人 和博士后研究员，他们在教师的指导下进行 在这个领域和其他医学相关领域的研究。 在 对原申请审查的反驳指出， 的博士培训计划结合了标准的课程方案， 基础生物化学，强调医学相关性，以及 结缔组织（软骨）生物化学专业课程。 自博士学位启动以来，1984年，26名候选人 获得了博士学位其中12人提出了他们的论文， 结缔组织（软骨）生物化学领域。 当前26 博士学生积极参加每周的部门研讨会， 与国内和国际公认的专家互动， 软骨研究，谁被邀请每两个月到该部门。 （8） 他们还没有选择他们的顾问;在剩下的14人中， 选择了博士学位-参与连接的教师的顾问 组织/软骨研究）。 通过重新起草的申请， 每年资助三名学生，为期五年（相当于43 学生年）。 博士后研究员的培训计划有一个选择的重点， 软骨生物化学和骨关节炎的基础上分配的 世界卫生组织。 培养博士后44名 来自地球仪的研究员。 目前有10名研究员在 部门（大约50%的过去或现在的研究员持有医学博士学位。度）。 每个博士后研究员被分配给一名教员，但范围更广。 通过每周讲习班、正式研讨会 与来访科学家的互动讨论和非正式讨论 组 博士后培训计划使研究员成为 一个调查小组的积极成员，学习个人的设计 研究战略，扩大他们的专业目标，监测和 教授研究生和医学院课程，并发展他们的写作 从出版物和赠款的技能。 它允许他们，当他们进入 科学的劳动力，为软骨做出有意义的贡献 生物化学 在未来五年内，寻求财政支持， 每年两个博士后奖学金（等于10个奖学金年）。 这个培训计划是独一无二的，在准备，并排，毕业 学生和博士后研究员的研究生涯。 这个新的NIH 培训补助金将使培训计划侧重于肌肉骨骼 研究，特别是软骨生物化学和 OA。