POPULATION BASED CASE CONTROL STUDY OF ORAL CANCER

描述：此应用程序请求指导临床科学家 发展奖(MCSDA)，支持在美国攻读博士学位 流行病学(DrPH)，同时仍是一名兼职牙科教员。 学习计划包括一个为期五年的综合培训计划 在临床流行病学中以口腔健康问题为导向 少数族裔人口。拟议的计划将使玛丽亚·罗莎博士 沃森将设立一个独立的临床和研究教职员工职位 在马里兰大学巴尔的摩牙科学校。 博士学位的学术和研究环境将是 约翰·霍普金斯大学流行病学系 公共卫生学院(JHU-SPH)。主要导师华生博士将 ASLO与马里兰大学的其他研究人员合作 巴尔的摩牙科学校。沃森博士的教师发展导师将是 儿科牙科主任詹姆斯·鲁尔医生 UMAB-DS，将通过协调她来监督她的教学培训 临床和教学机会。 该计划建议将重点放在以下方面的一般技能和知识 流行病学以及重要的少数民族口腔健康研究问题， 包括：1)获取适当的少数群体样本的技术 人口；2)开发适合文化的工具；以及3) 验证测量仪器的技术。所描述的课程作业 是一个典型的为期两年的高强度课程，在流行病学和 生物统计学，随后对前两项进行了全面检查 好几年了。博士论文研究是在02年完成的，并在 01-05年度提供辅助研究和教学活动。 提出的具体研究计划包括两个方面：1.研究和分析 与其他人相比，拉美裔人存活的决定因素；以及2. 青海省口腔癌危险因素的病例对照研究 西班牙裔。研究的具体目的是：1)评估风险 口腔癌的致癌因素(例如，饮食、烟草、酒精和其他文化 练习)拉美裔和白人之间的差异；2)确定和比较口语 拉美裔和白人之间的癌症存活率和死亡率； 评估早期筛查不足与低水平的关系 了解口腔癌知识和口腔癌死亡率。建议数 设计是一项利用新墨西哥州肿瘤病例的病例对照研究 注册表。将通过随机数字拨号(RDD)选择控件。 面试将通过电话进行，由来自 新墨西哥州肿瘤登记处，使用结构化问卷，将 是专门为这项研究设计的。拟议的研究项目将 提高对流行性出血热的描述流行病学和病因学的认识 口腔癌，特别是与发病率、患病率、 少数群体的存活率、特定死亡率和风险因素。

DESCRIPTION: This application requests a Mentored Clinical Scientist Development Award (MCSDA) to support the pursuit of a doctoral program in epidemiology (DrPH) while remaining a part-time dental faculty member. The plan of study consists of a five-year program of integrated training in clinical epidemiology that is oriented towards oral health issues in minority populations. The proposed program will enable Dr. Maria Rosa Watson to establish an independent clinical and research faculty position at the University of Maryland at Baltimore Dental School. The academic and research environment for the doctoral degree will be centered at the Department of Epidemiology, Johns Hopkins University School of Public Health (JHU-SPH). The primary mentor, Dr. Watson will aslo collaborate with other investigators at the University of Maryland at Baltimore Dental School. Dr. Watson's faculty development mentor will be Dr. James Rule, the Chairman of the Department of Pediatric Dentistry at UMAB-DS, who will supervise her pedagogical training by coordinating her clinical and teaching opportunities. This program proposes to focus on general skills and knowledge in epidemiology as well as on important minority oral health research issues, including: 1) techniques for obtaining adequate samples of minority populations; 2) development of culturally appropriate instruments; and 3) techniques for validating survey instruments. The course work described is a typical intensive two years of course work in epidemiology and biostatistics, followed by comprehensive examinations over the first two years. The doctoral thesis research follows in year 02, supplemented in years 01-05 with complementary research and teaching activities. The specific research plan proposed includes two studies, 1. and analysis of the determinants of survival in Hispanics compared to to others; and 2. a population-based case-control study of risk factors for oral cancer in Hispanics. The specific aims of the study are: 1) to assess the risk factors for oral cancer (e.g., diet, tobacco, alcohol, and other cultural practices) between Hispanics and Whites; 2) to determine and compare oral cancer survival and mortality rates between Hispanics and Whites; and 3) to evaluate the relationship between lack of early screenings, low level of oral cancer knowledge and oral cancer mortality rates. The proposed design is a case-control study utilizing cases from the New Mexico Tumor Registry. Controls will be selected by Random Digit Dialing (RDD). Interviews will be conducted by phone by experienced interviewers from the New Mexico Tumor Registry, using a structured questionnaire that will be specifically designed for this study. The proposed research project will enhance the understanding of the descriptive epidemiology and etiology of oral cancer, in particular as it pertains to incidence, prevalence, survival, and specific mortality and risk factors in minority populations.