MULTIDISCIPLINARY TRAINING IN ENVIRONMENTAL TOXICOLOGY

在本申请中描述的多学科计划培养出具有环境毒理学基础知识的科学家，以及在以系为基础的毕业计划中获得的研究专业知识。博士前实习生必须满足他们所在部门的全部博士要求，并完成由环境毒理学研究所(IET)管理的环境毒理学多学科博士项目的课程作业、研究和互动方面的工作。该学位通过列出环境毒理学(如生物化学-环境毒理学博士)来认可培训的两面性，该项目的毕业生在解决复杂的环境问题过程中拥有良好的研究能力并与其他科学家互动，这些问题需要合作、多学科的方法。15名培训教师在四个系博士项目(药理学和毒理学、生物化学、食品科学和人类营养学、动物学)中进行博士前培训。作为多学科环境毒理学博士项目所要求的讲授、面向毒理学的课程，增加了系内的环境毒理学教育和环境毒理学研究培训。IET提供的课程作业和不那么正式的多学科互动和活动提供了比个别部门课程更广泛的知识范围。学员的研究主题包括：器官系统(如肝脏、免疫、内分泌、神经、呼吸)、致癌、生殖和食品安全等与机制相关的毒理学。此外，还提供了关于用于识别和量化毒性反应的现代分析技术的研究培训。博士后实习生在一名(或多名)培训教师的实验室进行研究，并通过参加IET活动和课程获得更多的环境毒理学经验。这项申请是为了支持6名博士后和3名博士后实习生，从而继续一个高效的多学科培训计划，将传统和非传统方法结合起来，为毕业生在环境毒理学领域做出重大贡献做准备。

The multi-disciplinary program describes in this application produces scientists having a base knowledge in environmental toxicology coupled with research expertise gained in a departmentally-based graduated program. Predoctoral trainees must meet the full Ph.D. requirements of their "home" department and complete the coursework, research and interactive aspects of the Multi-disciplinary Ph.D. Program in Environmental Toxicology administered by the Institute for Environmental Toxicology (IET). The degree awarded recognizes the dual nature of the training by listing the department-environmental toxicology (e.g., Ph.D. in Biochemistry-Environmental Toxicology), Graduates of the program are well-equipped to conduct research and interact with other scientists in the course of solving complex environmental problems that require collaborative, multi-disciplinary approaches. Fifteen training faculty conduct predoctoral training in four departmental Ph.D. programs (Pharmacology and Toxicology, Biochemistry, Food Science and Human Nutrition, Zoology). Added to the department- based education and environmental toxicology research training in departments as didactic, toxicology-oriented courses required by the Multi-disciplinary Ph.D. Program in Environmental Toxicology. This coursework and less formal multi-disciplinary interactions and activities provided by the IET imparts a wider scope of knowledge than is available within individual departmental programs. Research topics for trainees are available in mechanisms-related toxicology encompassing: organ systems (e.g., hepatic, immune, endocrine, neuronal, respiratory), carcinogenesis, reproduction and food safety. In addition, research training is available on modern analytical techniques used to identify and quantitate toxic responses. Postdoctoral trainees conduct research in the laboratory of one (or more) of the training faculty and gain additional environment toxicology experience through participation in IET activities and courses. This application is for support of six predoctoral and three postdoctoral trainees, thereby continuing a highly effective multi- disciplinary training program which mixes traditional and non- traditional approaches to prepare graduates to make significant contributions to the field of environmental toxicology.