MRI: Acquisition of a LC/MS/MS for Multidisciplinary Environmental Studies and Training at Tennessee State University

MRI：在田纳西州立大学获得用于多学科环境研究和培训的 LC/MS/MS

• 批准号: 2018104
• 负责人: Lin Li
• 金额: $ 14万
• 依托单位: Tennessee State University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-01 至 2023-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2018104&HistoricalAwards=false
• 关键词: MRI; Acquisition; LC; MS; Multidisciplinary

An instrument that pairs liquid chromatography with triple quadrupole mass spectrometry (LC-MS/MS) has the capability to analyze multiple compounds and their chemical structures in complex mixtures. Acquisition of such an instrument enables fundamental multidisciplinary research at Tennessee State University by researchers from environmental engineering, chemistry, food science, soil science, and biology. Key research activities include efforts to advance knowledge on: 1) degradation products of insecticides in the environment, 2) water treatment processes to remove pharmaceuticals, 3) processes that degrade toxins in water, 4) absorption of insecticides by nursery pests, and 5) pesticide residues in engineered food. The instrumentation will become a key element of TSU’s research infrastructure. The LC-MS/MS will be used in undergraduate and graduate courses and will promote partnerships and collaborative activities with surrounding universities and research centers.This advanced LC-MS/MS instrumentation consists a triple quadrupole analyzer with a mass range up to 3,000 m/z and a detection limit of ng/l level. This capability will allow environmental engineering researchers to determine seven neonicotinoid residues and possible degradation products in soil and water, enabling discovery of the fate and transport of neonicotinoids in the environment. Researchers will monitor emerging contaminants, including perfluorinated compounds in groundwater, cyanotoxins in surface waters, and residuals of pharmaceuticals and personal care products in wastewater, improving understanding of the effect of degradation processes due to biodegradation, photolysis, and hydrolysis on the behavior of emerging contaminants. The LC-MS/MS will be used to characterize the residual analysis of insecticides in the development of effective treatment methods of soil and container media for nursery pests including Chrysobothris, Japanese beetle, and fire ants. The LC-MS/MS will allow food science researchers to characterize the structure and functionality change of bioactive polysaccharides to learn more about the stability and shelf life of engineered food. Researchers in agriculture will use the equipment to study complex pesticide residues.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

将液相色谱与三倍四极杆质谱法（LC-MS/MS）配对的仪器具有分析多种化合物及其化学结构的能力。通过环境工程，化学，食品科学，土壤科学和生物学的研究人员，获取这种工具可以在田纳西州立大学的基本多学科研究。关键的研究活动包括促进知识的努力：1）仪器在环境中的降解产物，2）水处理过程以去除药物，3）降解水中毒素的过程，4）托儿所害虫造成仪器的痛苦，以及5）工程食品中的农药保留。该仪器将成为TSU研究基础设施的关键要素。 LC-MS/MS将用于本科和研究生课程，并将促进与周围大学和研究中心的合作伙伴关系和协作活动。该高级LC-MS/MS仪器由三倍四倍分析仪组成，由三倍的四倍分析仪组成，质量范围为3,000 m/z，以及NG/L水平的检测限制。该能力将使环境工程研究人员能够确定七个新烟碱的残基和土壤和水中可能的定义产品，从而能够发现环境中新烟碱的命运和运输。研究人员将监测新兴污染物，包括地下水中的全氟化化合物，地表水中的氰毒素以及废水中的药物和个人护理产品的残留物，从而提高了对由于生物降解，光解，光解，光解和对Emerging contaminains的行为的降解过程的理解。 LC-MS/MS将用于表征杀虫剂在开发有效的土壤和容器培养基的有效治疗方法中的残留分析，用于托儿所的害虫，包括Chrysobothris，日本甲虫和消防蚂蚁。 LC-MS/MS将使食品科学研究人员能够表征生物活性多糖的结构和功能变化，以了解有关工程食品的稳定性和保质期的更多信息。一致性研究人员将使用该设备研究复杂的农药保留率。该奖项反映了NSF的法定任务，并通过使用基金会的知识分子优点和更广泛的影响审查标准来评估被认为是宝贵的支持。

项目成果

2022 AEESP Research and Education Conference

2022年AEESP研究与教育会议

• 发表时间: 2022
• 期刊: AEESP
• 作者: Kirwa, S.;Gardiner, A.;Painter, R.;Al Janabi, A.;and Li, L.
• 通讯作者: and Li, L.

Photodegradation of Neonicotinoid Insecticides Nitenpyram, Thiacloprid, and Acetamiprid in Water and Soil Environments

• DOI: 10.1007/s00128-024-03975-x
• 发表时间: 2024-12-01
• 期刊: BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY
• 影响因子: 2.7
• 作者: Li，Yang;Li，Yadong
• 通讯作者: Li，Yadong