A genome-wide association study of endometrial cancer

子宫内膜癌的全基因组关联研究

• 批准号: nhmrc : 552402
• 负责人: Prof Amanda Spurdle
• 金额: $ 71.1万
• 依托单位: Queensland Institute of Medical Research
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2009
• 资助国家: 澳大利亚
• 起止时间: 2009-01-01 至 2011-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/genome-wide-association-endometrial-cancer/94689
• 关键词: genome; wide; association; study; endometrial

Endometrial cancer (uterine-womb cancer) is the most common invasive gynaecological cancer in Australia. Each year more than 1400 women are affected by the condition. The non-biased approach of our large study will identify genes that increase risk of this cancer, to provide information for future targeted therapies to prevent progression, and large-scale studies investigating how these genes interact with environmental factors such as hormone replacement therapy and obesity to cause disease.

子宫内膜癌（子宫-子宫癌）是澳大利亚最常见的侵袭性妇科癌症。每年有1400多名妇女受到这种疾病的影响。我们的大型研究的无偏见方法将确定增加这种癌症风险的基因，为未来的靶向治疗提供信息，以防止进展，以及调查这些基因如何与环境因素相互作用的大规模研究，如激素替代疗法和肥胖引起疾病。