A helminth-derived peptide is a novel prophylactic and therapeutic treatment for autoimmune disease

蠕虫衍生肽是一种新型的自身免疫性疾病的预防和治疗方法

• 批准号: nhmrc : GNT1087341
• 负责人: A/Pr Bronwyn O'Brien
• 金额: $ 63.87万
• 依托单位: University of Technology Sydney
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2015
• 资助国家: 澳大利亚
• 起止时间: 2015-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/helminth-derived-peptide-autoimmune-disease/1345700
• 关键词: helminth; derived; peptide; novel; prophylactic

Parasitic worms (helminths) secrete molecules that possess a remarkable ability to skew the mammalian immune system towards anti-inflammatory responses. We have expoited a novel peptide secreted by helminths, which offers tremendous potential for the development of novel prophylactic and therapeutic treatments for a range of immune-mediated conditions. The overarching aim of this project is to further elucidate the mechanism of action and to determine the peptide’s clinical application.

寄生虫（蠕虫）分泌的分子具有非凡的能力，使哺乳动物的免疫系统偏向抗炎反应。我们已经鉴定出一种由蠕虫分泌的新型肽，其为开发用于一系列免疫介导的病症的新型预防性和治疗性治疗提供了巨大的潜力。该项目的首要目标是进一步阐明作用机制并确定肽的临床应用。