STRUCTURAL STUDIES OF PROTEINS

本提案的目标是收集数据并确定一个或 正在进行的八个不同项目的更多结构， 威斯康星州的黑兹尔霍尔顿博士的实验室和 伊万·雷蒙。 这一联合提案反映了一种努力， 有效利用了一个非常强大的X射线源。 的项目 涵盖了一系列问题，包括：转座酶/dsDNA复合物， 天冬酰胺合成酶，甲苯-4-单加氧酶：亚基D， 磷酸乙酸水解酶，苯丙氨酸脱氢酶，肌球蛋白S1 dC、卡那霉素核苷酸转移酶和ATP：类咕啉腺苷 转移酶（CobA）。 计划在一个 对于那些已经在较低的波长下解决的项目， 分离或用于蛋白质的分子复合物， 已经知道了。 在BioCARS Station 14-BM-D上收集数据。

The goal of this proposal is to collect data and determine one or more structures for eight different projects that are underway at the University of Wisconsin in the laboratories of Drs. Hazel Holden and Ivan Rayment. This joint proposal reflects an effort to make efficient useage of an enormously powerful X-ray source. The projects cover a range of problems including; a transposase/dsDNA complex, Asparagine Synthetase, toluene-4-monooxygenase: subunit D, Phosphonoacetate Hydrolase, Phenylalanine Dehydrogenase, Myosin S 1 dC, Kanamycin nucleotidyl transferase, and ATP:corrinoid adenosyl transferase (CobA). It is planned to collect accurate data at a single wavelength for those projects that have been solved at lower resolution or for molecular complexes for proteins whose fold is already known. Data collection on BioCARS Station 14-BM-D.