RELATIONSHIP OF AGE TO CIRCADIAN DESYNCHRONY IN PERMANENT NIGHT SHIFT WORK

长期夜班工作中年龄与昼夜节律不同步的关系

• 批准号: 6116938
• 负责人: ROBERT L SACK
• 金额: $ 3.13万
• 依托单位: OREGON HEALTH & SCIENCE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-12-01 至 1999-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6116938
• 关键词: aging; behavioral /social science research tag; circadian rhythms; clinical research; environmental adaptation; hormone therapy; human subject; human therapy evaluation; melatonin; occupations; psychophysiology; sleep

The overall goal is to understand the physiological basis for the reduced tolerance to permanent night shift work that is commonly associated with aging, and to attempt to improve adaptation to permanent night work with melatonin administration. Appropriately-timed melatonin administration will be tested as a method to improve adaptation to night shift work by correcting any phase angle disturbance between sleep and underlying circadian rhythms.

总体目标是了解减少的生理基础