课题基金 / 基金详情

GENETIC RELATIONSHIPS BETWEEN NIDDM AND ATHEROSCLEROSIS

GENETIC RELATIONSHIPS BETWEEN NIDDM AND ATHEROSCLEROSIS
NIDDM 与动脉粥样硬化之间的遗传关系
批准号：
6219918
负责人：
LESLIE RAFFEL
金额：
$0.1万
依托单位：
LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER
依托单位国家：
美国
项目类别：
财政年份：
1998
资助国家：
美国
项目状态：
已结题
起止时间：
1998-12-01 至 1999-11-30
来源：
https://reporter.nih.gov/project-details/6219918
关键词：
Hispanic Americans atherosclerosis clinical research coronary artery coronary disorder disease /disorder proneness /risk family genetics genetic disorder human genetic material tag human subject noninsulin dependent diabetes mellitus tissue /cell culture

项目摘要

项目成果

LESLIE RAFFEL的其他基金

相似基金

相关文献

中文摘要
翻译
尽管患有非胰岛素依赖型糖尿病(NIDDM)的个体患冠状动脉疾病的风险显著增加，并且NIDDM在拉美裔美国人中的发生率增加，但这一群体中动脉粥样硬化的发生比非西班牙裔白种人糖尿病个体要少得多。这一观察的遗传学基础正在西班牙裔NIDDM患者家庭中进行测试，这些患者有或没有冠状动脉疾病。淋巴母细胞系的建立是为了在组织培养设施中进行DNA研究。
英文摘要
Although individuals with noninsulin dependent diabetes mellitus (NIDDM) have a significantly higher risk for coronary artery disease and NIDDM occurs with increased frequency in Hispanic Americans, the occurrence of atherosclerosis is much less in this group than in non-Hispanic Caucasian diabetic individuals. The genetic basis for this observation is being tested in the families of Hispanic NIDDM patients with and without coronary disease. Lymphoblastoid cell lines are established for DNA studies in the Tissue Culture Facility.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
GENNID--NIDDM FAMILY ACQUISITION CENTER
GENETIC RELATIONSHIPS BETWEEN NIDDM AND ATHEROSCLEROSIS
MOLECULAR GENETICS OF HYPERTENSION
DIABETES PREVENTION TRIAL-TYPE 1 DIABETES (DPT-1)
海外基金