课题基金 / 基金详情

MOLECULAR GENETICS OF HYPERTENSION

MOLECULAR GENETICS OF HYPERTENSION
高血压的分子遗传学
批准号：
6306674
负责人：
LESLIE RAFFEL
金额：
$0.1万
依托单位：
LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER
依托单位国家：
美国
项目类别：
财政年份：
1999
资助国家：
美国
项目状态：
已结题
起止时间：
1999-12-01 至 2000-11-30
来源：
https://reporter.nih.gov/project-details/6306674
关键词：
Mexican Americans cell line clinical research familial hypertension family genetics gene expression human genetic material tag human subject insulin sensitivity /resistance molecular genetics phenotype tissue /cell culture tissue /cell preparation

项目摘要

项目成果

LESLIE RAFFEL的其他基金

相似基金

相关文献

中文摘要
翻译
目的是确定影响血压的基因，从而在墨西哥裔美国家庭中导致高血压的发生。由于胰岛素抵抗在高血压中的重要性，以及墨西哥裔美国人中胰岛素抵抗的高患病率，本研究非常重视胰岛素抵抗作为这一民族的中间表型的检查。在南加州大学招募患者，在锡达斯-西奈的组织培养设施建立用于DNA研究的淋巴母细胞系。
英文摘要
The goal is to identify genes which influence blood pressure and thus are responsible for the development of hypertension in Mexican American families. Because of the importance of insulin resistance in hypertension, as well as the high prevalence of insulin resistance in the Mexican American population, the study places great emphasis on examination of insulin resistance as an intermediate phenotype in this ethnic group. Patients are recruited at USC and lymphoblastoid cell lines for DNA studies are established in the Tissue Culture Facility here at Cedars-Sinai.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
GENNID--NIDDM FAMILY ACQUISITION CENTER
GENETIC RELATIONSHIPS BETWEEN NIDDM AND ATHEROSCLEROSIS
MOLECULAR GENETICS OF HYPERTENSION
DIABETES PREVENTION TRIAL-TYPE 1 DIABETES (DPT-1)
海外基金