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DDAVP INDUCED HYPONATREMIA FOR TREATMENT OF OLIGOHYDRAMNIOS

DDAVP INDUCED HYPONATREMIA FOR TREATMENT OF OLIGOHYDRAMNIOS
DDAVP 诱导低钠血症治疗低钠血症
批准号：
6117195
负责人：
Michael Glenn Ross
金额：
$3.89万
依托单位：
LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER
依托单位国家：
美国
项目类别：
财政年份：
1998
资助国家：
美国
项目状态：
已结题
起止时间：
1998-12-01 至 1999-11-30
来源：
https://reporter.nih.gov/project-details/6117195
关键词：
amniotic fluid clinical research female hormone therapy human pregnant subject human subject human therapy evaluation hyponatremia pregnancy disorder urination vasopressins

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英文摘要
Despite the significant consequences of oligohydramnios there are few clinical approaches to increase amniotic fluid. Recent studies indicate the potential utility of a novel treatment for oligohydramnios using maternal DDAVP administration to increase fetal urine flow. DDAVP causes the maternal and fetal kidney to excrete a lower volume of more concentrated urine. As the mother retains water, maternal and fetal plasma osmolality is reduced and fetal urine flow is increased. This study will examine the long term effect of maternal DDAVP.
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