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COMPARATIVE BACKBONE DYNAMICS OF NTRC IN ITS ACTIVE & INACTIVE CONFORMATIONS

COMPARATIVE BACKBONE DYNAMICS OF NTRC IN ITS ACTIVE & INACTIVE CONFORMATIONS
NTRC 活动状态下的骨干动力学比较
批准号:
6121011
负责人:
BRIAN F VOLKMAN
金额:
$1.54万
依托单位国家:
美国
项目类别:
财政年份:
1999
资助国家:
美国
项目状态:
已结题
起止时间:
1999-03-01 至 2000-02-29

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中文摘要
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英文摘要
The major goal of this project is to: Determine the metabolic capabilities of the human uroepithelial cells, for activation of 4-aminobiphenyl and its N-hydroxy metabolites. Identify which of the proximate metabolites are converted to reactive electrophilic species. Identify the DNA-adducts that are generated by interaction of the ultimate electrophile with the DNA. Evaluate the biological effects of interaction of 4-aminobiphenyl derivatives with urothelial DNA - at the level of (A) mutation and (B) neoplastic transformation.
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PULSE SEQUENCE DEVELOPMENT
  • 批准号:
    6309181
  • 项目类别:
  • 资助金额:
    $0.75万
  • 财政年份:
    2000
  • 负责人:
    BRIAN F VOLKMAN
  • 依托单位:
MAGNETIC ALIGNMENT OF CLOSTRIDIUM PASTEURIANUM RUBREDOXIN
  • 批准号:
    6121012
  • 项目类别:
  • 资助金额:
    $7.33万
  • 财政年份:
    1999
  • 负责人:
    BRIAN F VOLKMAN
  • 依托单位:
STRUCTURE OF HUMAN CHEMOKINE LYMPHOTACTIN
  • 批准号:
    6121010
  • 项目类别:
  • 资助金额:
    $0.67万
  • 财政年份:
    1999
  • 负责人:
    BRIAN F VOLKMAN
  • 依托单位:
PULSE SEQUENCE DEVELOPMENT
  • 批准号:
    6121008
  • 项目类别:
  • 资助金额:
    $1.15万
  • 财政年份:
    1999
  • 负责人:
    BRIAN F VOLKMAN
  • 依托单位:
海外基金