课题基金 / 基金详情

MOLECULAR BIOLOGY OF GASTRIC MUCOSAL CELLS

MOLECULAR BIOLOGY OF GASTRIC MUCOSAL CELLS
胃粘膜细胞的分子生物学
批准号：
6244563
负责人：
Tadataka Yamada
金额：
$2.22万
依托单位：
UNIVERSITY OF MICHIGAN AT ANN ARBOR
依托单位国家：
美国
项目类别：
财政年份：
1997
资助国家：
美国
项目状态：
已结题
起止时间：
1997-02-20 至 1997-11-30
来源：
https://reporter.nih.gov/project-details/6244563
关键词：
carbonate dehydratase computer assisted sequence analysis gastric mucosa gastrins gene expression hormone receptor molecular cloning peptide hormone protein structure function sodium potassium exchanging ATPase somatostatin

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中文摘要
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英文摘要
This study is directed at examining the biosynthesis post-translational processing and biological activity of peptide hormones in the gut as they interact to regulate gastric acid secretion. The focus of this protocol will be to explore the molecular biology of the enzymes carbonic anhydrase and H(+)K(+)-ATPase, as well as the hormones gastrin and somatostatin. We propose to utilize the GCRC computer to assist us with gene sequence analysis for comparison with other biological substances.
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MOLECULAR BIOLOGY OF GASTRIC MUCOSAL CELLS
GASTROINTESTINAL SIGNIFICANCE OF GASTRIN REGULATION
GASTROINTESTINAL HORMONE RESEARCH CENTER CORE
GASTROINTESTINAL HORMONE RESEARCH CENTER CORE