课题基金 / 基金详情

GROWTH RETARDATION--HPA AXIS RESPONSE TO CRH AND CORTISOL CHALLENGES

GROWTH RETARDATION--HPA AXIS RESPONSE TO CRH AND CORTISOL CHALLENGES
生长迟缓——HPA 轴对 CRH 和皮质醇挑战的反应
批准号：
6244565
负责人：
Delia M Vazquez
金额：
$2.22万
依托单位：
UNIVERSITY OF MICHIGAN AT ANN ARBOR
依托单位国家：
美国
项目类别：
财政年份：
1997
资助国家：
美国
项目状态：
已结题
起止时间：
1997-02-20 至 1997-11-30
来源：
https://reporter.nih.gov/project-details/6244565
关键词：
behavioral /social science research tag child (0-11) clinical research corticotropin releasing factor cortisol hormone regulation /control mechanism human subject hypothalamic pituitary axis pituitary adrenal axis pituitary dwarfism postnatal growth disorder psychological stressor somatotropin stress

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中文摘要
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英文摘要
This proposal studies the growth hormone (GH) and hypothalamic pituitary adrenal (HPA) axis physiology in children with short stature and psychosocial dwarfs. The aim is to address the possibility that: repeated psychological stress during development activates the HPA axis; leads to an abnormal regulation of its elements and this ultimately is conducive to a tonic inhibition on GH release and growth failure.
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ALTERING NEUROPLASTICITY DURING DEVELOPMENT
DEPRESSION RISK, INFANT-MOTHER ATTACHMENT AND CORTISOL
DEPRESSION RISK, INFANT-MOTHER ATTACHMENT AND CORTISOL
DEPRESSION RISK, INFANT-MOTHER ATTACHMENT AND CORTISOL