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FETAL STEM CELL TRANSPLANTATION FOR ALPHA THALASSEMIA

FETAL STEM CELL TRANSPLANTATION FOR ALPHA THALASSEMIA
胎儿干细胞移植治疗α地中海贫血
批准号:
6246110
负责人:
Anthony R. Hayward
金额:
$1.71万
依托单位国家:
美国
项目类别:
财政年份:
1997
资助国家:
美国
项目状态:
已结题
起止时间:
1997-03-20 至 1997-11-30

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项目成果

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中文摘要
翻译
本研究是基于人类同种异体移植的假设
英文摘要
This study is based on the hypothesis that humans grafted with allogeneic bone marrow stem cells at 12-13 weeks of age will develop stable and long lasting chimerism. This hypothesis derives from the observation that T cells do not peripheralize from the human fetal thymus until 14 weeks of gestation, together with the finding that animals grafted with stem cells, before they have T cells, develop specific immunologic tolerance. Our studies will generate data on which fetal grafts of genetically engineered cells might be based.
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TRAINING PROGRAM IN PEDIATRIC IMMUMOLOGY
  • 批准号:
    6149809
  • 项目类别:
  • 资助金额:
    $14.95万
  • 财政年份:
    2000
  • 负责人:
    Anthony R. Hayward
  • 依托单位:
CELLULAR IMMUNITY TO CRYPTOSPORIDIUM PARVUM
  • 批准号:
    2887373
  • 项目类别:
  • 资助金额:
    $14.29万
  • 财政年份:
    1998
  • 负责人:
    Anthony R. Hayward
  • 依托单位:
CELLULAR IMMUNITY TO CRYPTOSPORIDIUM PARVUM
  • 批准号:
    2712314
  • 项目类别:
  • 资助金额:
    $13.88万
  • 财政年份:
    1998
  • 负责人:
    Anthony R. Hayward
  • 依托单位:
SPECIFIC IMMUNITY DEVELOPMENT IN HUMAN NEWBORNS
  • 批准号:
    6114924
  • 项目类别:
  • 资助金额:
    $1.99万
  • 财政年份:
    1998
  • 负责人:
    Anthony R. Hayward
  • 依托单位:
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