INHALED STEROIDS TO PREVENT CHRONIC LUNG DISEASE IN INTUBATED PREMATURE INFANTS

吸入类固醇预防插管早产儿的慢性肺病

• 批准号: 6246074
• 负责人: SUSAN F TOWNSEND
• 金额: $ 1.71万
• 依托单位: UNIVERSITY OF COLORADO DENVER
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-03-20 至 1997-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6246074
• 关键词: chemoprevention; clinical research; drug adverse effect; human subject; human therapy evaluation; inhalation drug administration; intravenous administration; premature infant human; respiratory distress syndrome of newborn; respiratory therapy; steroids

This study will determine whether early treatment of intubated extremely low birhtweight premature infants with respiratory distress with inhaled steroids will diminish the use of more toxic therapy with high-dose intravenous steroids; and whether such treatment will shorten the duration of mechanical ventilation and decrease the incidence of chronic lung disease. Safety of therapy with inhaled steroids will be evaluated and comapred to treatment with intravenous steroids.

这项研究将确定是否对插管的患者进行早期治疗 吸入性呼吸困难的低出生体重早产儿 类固醇将减少高剂量毒性更强的治疗的使用 静脉注射类固醇；以及这种治疗是否会缩短持续时间 机械通气并降低慢性肺病的发生率 疾病。 将评估吸入类固醇治疗的安全性并 与静脉注射类固醇治疗相比。