Disorders of Human Sexual Development

性发育障碍（dsd）非常普遍，通常会导致不孕、生殖器异常、性别分配错误和长期的心理创伤。在这个项目中，我们将汇集我们在人类分子遗传学，小鼠发育生物学和蛋白质化学方面的专业知识，以确定对性别决定和性腺发育重要的基因，并发现它们如何促进DSD，以改善DSD患者的临床护理。

Disorders of sexual development (DSDs) are surprisingly common, and often result in infertility, genital abnormalities, gender mis-assignment and long-term psychological trauma. In this Program we will pool our expertise in human molecular genetics, mouse developmental biology and protein chemistry to identify genes important for sex determination and development of the gonads, and discover how they contribute to DSD, in order to improve clinical care to patients with DSD.