Disorders of Sex Development

性发育障碍（DSDs）是令人惊讶的常见疾病，通常会导致不育，生殖器异常，性别错误分配和长期的心理创伤。这项研究结合了人类分子遗传学，小鼠发育生物学和蛋白质化学的专业知识，以确定对性别决定和性腺发育重要的基因，并发现它们如何有助于DSD，以改善对DSD患者的临床护理。

Disorders of sex development (DSDs) are surprisingly common, and often result in infertility, genital abnormalities, gender mis-assignment and long-term psychological trauma. This research combines expertise in human molecular genetics, mouse developmental biology and protein chemistry to identify genes important for sex determination and development of the gonads, and discover how they contribute to DSD, in order to improve clinical care to patients with DSD.