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EFFECTS & SAFETY OF ENDOTHELIN RECEPTOR ANTAGONIST BMS 193884 IN HEAR

EFFECTS & SAFETY OF ENDOTHELIN RECEPTOR ANTAGONIST BMS 193884 IN HEAR
效果
批准号：
6265045
负责人：
DONNA M MANCINI
金额：
$0.04万
依托单位：
COLUMBIA UNIVERSITY HEALTH SCIENCES
依托单位国家：
美国
项目类别：
财政年份：
1998
资助国家：
美国
项目状态：
已结题
起止时间：
1998-12-01 至 1999-11-30
来源：
https://reporter.nih.gov/project-details/6265045
关键词：
clinical research dosage drug screening /evaluation endothelin heart disorder chemotherapy heart failure hormone receptor human subject inhibitor /antagonist

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中文摘要
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英文摘要
Endothelin is a naturally occurring hormone which is a potent vasoconstrictor. BMS-193884 is a highly selective endothelin receptor antagonist. The primary indication for this drug will be as an adjunct to standard triple therapy in the treatment of heart failure by vasodilation. The primary objective of this study is to evaluate the dose related hemodynamic response of BMS-193884.
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