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POTENTIAL INTERACTIONS BETWEEN PACLITAXEL & PROTEASE INHIBITORS IN KS

POTENTIAL INTERACTIONS BETWEEN PACLITAXEL & PROTEASE INHIBITORS IN KS
紫杉醇之间的潜在相互作用
批准号：
6265431
负责人：
BRUCE J DEZUBE
金额：
$2.98万
依托单位：
BETH ISRAEL DEACONESS MEDICAL CENTER
依托单位国家：
美国
项目类别：
财政年份：
1998
资助国家：
美国
项目状态：
已结题
起止时间：
1998-12-01 至 1999-11-30
来源：
https://reporter.nih.gov/project-details/6265431
关键词：
HIV infections Kaposi's sarcoma clinical research clinical trial phase I dosage drug adverse effect drug interactions drug screening /evaluation human subject human therapy evaluation intravenous administration paclitaxel protease inhibitor

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中文摘要
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英文摘要
1) To determine whether the expected exposure to Paclitaxel will be produced by the delivered dose when given in conjunction with protease inhibitors; 2) to evaluate the objective response rate of intravenous Paclitaxel in patients with advanced AIDS-related Kaposi's sarcoma ; 3) to define toxicity profiles of IV Paclitaxel administration; 4) to evaluate the effect of IV Paclitaxel on the clinical course of HIV infection.
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