DIABETES PREVENTION TRIAL--TYPE 1

糖尿病预防试验-I型（DPT）是一项多中心，NIH 赞助的研究，旨在测试的假设，干预期间， I型糖尿病的前驱期可延迟其临床发作。 对胰岛素依赖型糖尿病患者的一级亲属进行筛查， 胰岛细胞抗体 那些检测呈阳性的人接受葡萄糖 耐受性试验 胰岛素减少的高危患者 将对葡萄糖的分泌反应随机分配到对照组、未处理的 组，以及将接受4天胰岛素输注的组 然后是长期皮下注射超长效胰岛素 随访访视 将每六个月评估一次葡萄糖耐量。 这项研究的结果将提供有关 管理有I型糖尿病风险的儿童和成人 糖尿病

The Diabetes Prevention Trial - Type I (DPT) is a Multicenter, NIH sponsored study designed to test the hypothesis that intervention during the prodromal phase of Type I diabetes may delay its clinical onset. First degree relatives of patients with IDDM are screened for the presence of islet cell antibodies. Those testing positive undergo glucose tolerance tests. High risk patients who have diminished insulin secretory responses to glucose are randomized to a control, untreated group, and to a group that will receive a 4 day infusion of insulin followed by chronic subcutaneous ultra lente insulin. Follow-up visits will assess the state of glucose tolerance every six months. The results of the study will provide important information regarding the management of children and adults at risk for the development of Type I diabetes.