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CORE--ASSAYS AND REAGENTS

CORE--ASSAYS AND REAGENTS
核心——测定和试剂
批准号:
6108393
负责人:
Alvin Rees Midgley
金额:
$13.11万
依托单位国家:
美国
项目类别:
财政年份:
1998
资助国家:
美国
项目状态:
已结题
起止时间:
1998-04-01 至 2000-03-31

项目摘要

项目成果

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中文摘要
翻译
检测试剂和试剂核心的总体目标是提供 本领域的分析方法、试剂、建议、培训、帮助,以及 服务的方式,将提高成本效益,质量, 主要研究者开展研究的及时性 项目具体来说,核心将:获取、清点和维护 符合条件的项目所需的充足的分析试剂库存( 包括开发、批量购买、索取礼品或化学 合成第一和第二多克隆和单克隆免疫原 抗体和抗体片段、标准品、其他参考品和质量 对照制剂和用放射性碘化物、生物素或 酶);表征和测试获得的试剂,并提供 符合条件的项目;满足低容量用户,个人的需求 实验室支持不足的用户,以及有其他需求的用户, 提供高质量的、具有成本效益的服务分析, 以结果为基础;采用先进的分析质量控制 所有活动的程序;维护绩效记录,库存, 提供的所有试剂和检测系统的文件 提供及时的信息、帮助和建议, 有效的方法;制定或以其他方式实施改进的、状态 本领域的测定方法和分析程序减少了 放射性同位素,并提供增加的特异性,灵敏度, 可靠性和易用性;提供质量控制评估, 向合格项目提供检测试剂盒和检测试剂盒;教授检测试剂盒 技术和免疫分析数据处理,并提供培训和 放射性和危险材料安全指令, 生物危害预防措施,实验室安全和卫生, 适用的法规遵从性。
英文摘要
The overall goal of the Assays and Reagents Core is to provide state of the art assay methods, reagents, advice, training, assistance, and service in ways that will increase the cost effectiveness, quality, and timeliness of research performed by principal investigators of eligible projects. Specifically, the Core will: obtain, inventory, and maintain adequate stocks of analytical reagents needed by eligible projects (this includes developing, purchasing in bulk, requesting gifts or chemically synthesizing immunogens, first and second polyclonal and monoclonal antibodies and antibody fragments, standards, other reference and quality control preparations, and tracers labeled with radioiodide, biotin or enzymes); characterize and test acquired reagents and make them available to eligible projects; meet the needs of low volume Users, individuals with inadequate laboratory support, and Users with other needs by providing high quality, cost-effective service assays on a samples-in, results-out basis; incorporate advanced analytical quality control procedures in all activities; maintain performance records, inventories, and documentation for all reagents and assay systems provided by the Core; provide timely information, assistance, and advice in utilizing the methods effectively; develop or otherwise implement improved, state of the art assay methods and analytical procedures that reduce the use of radioactive isotopes and provide increased specificity, sensitivity, reliability and ease of use; provide quality control assessments for assays and assay kits provided to eligible projects and; teach assay technology and immunoassay data processing, and provide training and instruction in radioactive and hazardous materials safety, in universal precautions for biohazards, in laboratory safety and sanitation, and in applicable regulatory compliance.
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海外基金